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Table 1—

Baseline characteristics in women who elected DMPA or low-dose COCs as initial method of contraception*

DMPACOCsP value
n 96 430  
Insulin treated during index pregnancy 12.5 13.1 0.88 
Age (years) 30.0 ± 5.5 29.0 ± 5.5 0.13 
BMI (kg/m230.4 ± 6.1 28.3 ± 4.4 0.002 
Parity 2.6 ± 1.6 2.3 ± 1.3 0.10 
Diabetes in family (%) 22.9 10.2 0.0007 
Breastfeeding (%) 22.9 <0.0001 
Fasting glucose (mg/dl) 91.5 ± 9.5 91.6 ± 10.5 0.97 
OGTT glucose AUC (mg · dl−1 · min−1 per 103) 15.8 ± 3.1 16.4 ± 3.4 0.11 
Impaired glucose tolerance§ 21 27 0.20 
Systolic blood pressure ( mmHg) 114.4 ± 14.3 112.2 ± 10.8 0.16 
Diastolic blood pressure (mmHg) 66.7 ± 10.2 67.5 ± 9.6 0.44 
Total cholesterol (mg/dl) 204.5 ± 41.7 206.1 ± 38.0 0.72 
HDL cholesterol (mg/dl) 38.6 ± 11.2 45.7 ± 12.0 <0.0001 
LDL cholesterol (mg/dl) 133.2 ± 32.5 126.0 ± 34.5 0.07 
Triglycerides (mg/dl) 157.0 ± 95.9 180.6 ± 102.1 0.01 
DMPACOCsP value
n 96 430  
Insulin treated during index pregnancy 12.5 13.1 0.88 
Age (years) 30.0 ± 5.5 29.0 ± 5.5 0.13 
BMI (kg/m230.4 ± 6.1 28.3 ± 4.4 0.002 
Parity 2.6 ± 1.6 2.3 ± 1.3 0.10 
Diabetes in family (%) 22.9 10.2 0.0007 
Breastfeeding (%) 22.9 <0.0001 
Fasting glucose (mg/dl) 91.5 ± 9.5 91.6 ± 10.5 0.97 
OGTT glucose AUC (mg · dl−1 · min−1 per 103) 15.8 ± 3.1 16.4 ± 3.4 0.11 
Impaired glucose tolerance§ 21 27 0.20 
Systolic blood pressure ( mmHg) 114.4 ± 14.3 112.2 ± 10.8 0.16 
Diastolic blood pressure (mmHg) 66.7 ± 10.2 67.5 ± 9.6 0.44 
Total cholesterol (mg/dl) 204.5 ± 41.7 206.1 ± 38.0 0.72 
HDL cholesterol (mg/dl) 38.6 ± 11.2 45.7 ± 12.0 <0.0001 
LDL cholesterol (mg/dl) 133.2 ± 32.5 126.0 ± 34.5 0.07 
Triglycerides (mg/dl) 157.0 ± 95.9 180.6 ± 102.1 0.01 

Data are means ± SD or frequency percent, unless otherwise indicated.

*

At initial postpartum visit for OGTT and selection of method of contraception.

From t test or χ2 or Fisher’s exact test. For triglycerides, log transformation was applied prior to t test.

Total area under glucose curve (AUC), calculated by trapezoid rule. §Impaired glucose tolerance defined by 2-h OGTT glucose ≥140 and ≤199 mg/dl.

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