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Table 2—

Events and all-cause mortality during 10 years of follow-up in patients divided according to HRV during deep breathing

Abnormal: HRV ≤10 bpmBorderline: HRV 11–14 bpmNormal: HRV ≥15 bpmUnadjusted HR (95% CI)*P value unadjusted HRAdjusted HR (95% CI)*P value adjusted HR
All patients 216 65 107     
Fatal/nonfatal cardiovascular events 85 (39) 6 (9) 6 (6) 8.7 (3.8–20.0) <0.0001 4.9 (2.1–11.5) <0.0001 
All-cause mortality 62 (29) 7 (11) 6 (6) 5.7 (2.5–13.1) <0.0001 — NS 
Patients with nephropathy 151 21 25     
Fatal/nonfatal cardiovascular events 72 (48) 4 (19) 2 (10) 7.7 (1.9–31.5) 0.002 6.4 (1.5–26.3) 0.010 
All-cause mortality 53 (35) 3 (12) 3 (14) 3.3 (1.0–10.7) 0.043 — NS 
Patients with normoalbuminuria 65 44 82     
Fatal/nonfatal cardiovascular events 13 (20) 2 (5) 4 (5) 4.4 (1.4–13.6) 0.009 — NS 
All-cause mortality 9 (14) 4 (9) 3 (4) 3.9 (1.0–14.3) 0.043 — NS 
Abnormal: HRV ≤10 bpmBorderline: HRV 11–14 bpmNormal: HRV ≥15 bpmUnadjusted HR (95% CI)*P value unadjusted HRAdjusted HR (95% CI)*P value adjusted HR
All patients 216 65 107     
Fatal/nonfatal cardiovascular events 85 (39) 6 (9) 6 (6) 8.7 (3.8–20.0) <0.0001 4.9 (2.1–11.5) <0.0001 
All-cause mortality 62 (29) 7 (11) 6 (6) 5.7 (2.5–13.1) <0.0001 — NS 
Patients with nephropathy 151 21 25     
Fatal/nonfatal cardiovascular events 72 (48) 4 (19) 2 (10) 7.7 (1.9–31.5) 0.002 6.4 (1.5–26.3) 0.010 
All-cause mortality 53 (35) 3 (12) 3 (14) 3.3 (1.0–10.7) 0.043 — NS 
Patients with normoalbuminuria 65 44 82     
Fatal/nonfatal cardiovascular events 13 (20) 2 (5) 4 (5) 4.4 (1.4–13.6) 0.009 — NS 
All-cause mortality 9 (14) 4 (9) 3 (4) 3.9 (1.0–14.3) 0.043 — NS 

Data are n or n (%) unless otherwise indicated.

*

Comparing patients with abnormal HRV to patients with a normal HRV within categories.

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