Skip to Main Content
Table 3—

Mean electrophysiology measures in extension-phase studies

Duloxetine (n = 73)
Routine care (n = 40)
BaselineEnd pointChangeBaselineEnd pointChange
Study HMAVa       
    Ulnar F wave (ms) 31.66 31.73 0.07 31.33 31.60 0.27 
    Ulnar distal sensory latency (ms) 3.37 3.42 0.05 3.42 3.44 0.01 
    Peroneal F wave (ms) 58.35 58.86 0.51 59.76 60.83 1.07 
    Peroneal CMAP (mV) 1.29 1.20 −0.09 1.30 1.21 −0.10 
 Duloxetine (n = 118)
 
  Routine care (n = 49)
 
  
Study HMAVb       
    Ulnar F wave (ms) 29.84 30.03 0.19 30.98 31.26 0.28 
    Ulnar distal sensory latency (ms) 3.32 3.29 −0.03 3.38 3.31 −0.07 
    Peroneal F wave (ms) 56.31 56.54 0.23 54.72 56.43 1.71* 
    Peroneal CMAP (mV) 1.47 1.44 −0.03 1.46 1.40 −0.06 
Duloxetine (n = 73)
Routine care (n = 40)
BaselineEnd pointChangeBaselineEnd pointChange
Study HMAVa       
    Ulnar F wave (ms) 31.66 31.73 0.07 31.33 31.60 0.27 
    Ulnar distal sensory latency (ms) 3.37 3.42 0.05 3.42 3.44 0.01 
    Peroneal F wave (ms) 58.35 58.86 0.51 59.76 60.83 1.07 
    Peroneal CMAP (mV) 1.29 1.20 −0.09 1.30 1.21 −0.10 
 Duloxetine (n = 118)
 
  Routine care (n = 49)
 
  
Study HMAVb       
    Ulnar F wave (ms) 29.84 30.03 0.19 30.98 31.26 0.28 
    Ulnar distal sensory latency (ms) 3.32 3.29 −0.03 3.38 3.31 −0.07 
    Peroneal F wave (ms) 56.31 56.54 0.23 54.72 56.43 1.71* 
    Peroneal CMAP (mV) 1.47 1.44 −0.03 1.46 1.40 −0.06 

Data are mean values from the two 12-month extension-phase studies in which electrophysiology parameters were measured. Only those patients that had baseline and postbaseline measurements in the same limb are included. For some parameters, the number of patients with measurements may be less than what is listed (n) if not all measurements were completed or if different limbs were used at baseline and end point.

*

P = 0.05 compared with the duloxetine group. No other between-group differences reached statistical significance. CMAP, compound muscle action potential.

Close Modal

or Create an Account

Close Modal
Close Modal