Table 2—

Clinical characteristics by duration of diabetes in 13,612 type 1 diabetic patients in the cross-sectional survey 2004

Total nDuration of diabetes
0–9 years10–19 years20–29 years30–39 years>40 years
n  1,685 3,127 3,530 2,752 2,518 
Age of debut (years)  21.6 ± 5.0 16.9 ± 7.2 14.9 ± 7.7 14.2 ± 7.7 12.2 ± 7.0* 
Age (years)  26.9 ± 5.0 31.6 ± 7.2 39.1 ± 8.3 48.3 ± 8.2 60.0 ± 8.5* 
Men (%)  58.9 55.2 55.4 53.5 50.8* 
A1C (%)  7.66 ± 1.43 8.02 ± 1.27 8.05 ± 1.19 8.04 ± 1.14 7.88 ± 1.08* 
A1C <7.0% (%)  35.9 20.6 18.5 17.0 20.7* 
Systolic BP (mmHg)  119.7 ± 11.8 122.1 ± 13.3 127.2 ± 15.7 133.5 ± 16.9 139.8 ± 17.2* 
Diastolic BP (mmHg)  72.0 ± 8.7 73.9 ± 8.7 75.0 ± 9.1 74.4 ± 8.8 71.5 ± 9.1* 
Pulse pressure (mmHg)  47.6 ± 10.7 48.2 ± 10.9 52.1 ± 12.9 59.1 ± 15.1 68.3 ± 16.2* 
BP <130/80 mmHg (%)  60.2 52.0 40.5 29.0 19.1* 
Antihypertensives (%)  4.4 10.8 31.0 52.0 66.5* 
Hypertension (%)  12.8 20.2 41.8 65.8 81.9* 
BMI (kg/m2 24.8 ± 4.3 25.4 ± 3.8 25.5 ± 3.7 25.4 ± 3.9 25.0 ± 3.8* 
Total cholesterol (mmol/l) 11,855 4.49 ± 0.89 4.67 ± 0.91 4.80 ± 0.91 4.93 ± 0.92 4.91 ± 0.88* 
Triglycerides (mmol/l) 11,358 1.12 ± 1.01 1.12 ± 0.90 1.11 ± 0.71 1.15 ± 0.78 1.13 ± 0.66 
HDL cholesterol (mmol/l) 11,219 1.47 ± 0.46 1.53 ± 0.45 1.61 ± 0.47 1.68 ± 0.53 1.74 ± 0.53* 
LDL cholesterol (mmol/l) 10,993 2.53 ± 0.76 2.64 ± 0.80 2.71 ± 0.78 2.74 ± 0.79 2.68 ± 0.76* 
Lipid-lowering drugs (%) 13,091 3.0 8.5 20.9 36.2 50.8* 
Smokers (%) 10,832 12.8 14.2 13.4 14.3 11.1 
ASA (%) 11,980 0.7 2.6 10.0 25.4 44.4* 
Total nDuration of diabetes
0–9 years10–19 years20–29 years30–39 years>40 years
n  1,685 3,127 3,530 2,752 2,518 
Age of debut (years)  21.6 ± 5.0 16.9 ± 7.2 14.9 ± 7.7 14.2 ± 7.7 12.2 ± 7.0* 
Age (years)  26.9 ± 5.0 31.6 ± 7.2 39.1 ± 8.3 48.3 ± 8.2 60.0 ± 8.5* 
Men (%)  58.9 55.2 55.4 53.5 50.8* 
A1C (%)  7.66 ± 1.43 8.02 ± 1.27 8.05 ± 1.19 8.04 ± 1.14 7.88 ± 1.08* 
A1C <7.0% (%)  35.9 20.6 18.5 17.0 20.7* 
Systolic BP (mmHg)  119.7 ± 11.8 122.1 ± 13.3 127.2 ± 15.7 133.5 ± 16.9 139.8 ± 17.2* 
Diastolic BP (mmHg)  72.0 ± 8.7 73.9 ± 8.7 75.0 ± 9.1 74.4 ± 8.8 71.5 ± 9.1* 
Pulse pressure (mmHg)  47.6 ± 10.7 48.2 ± 10.9 52.1 ± 12.9 59.1 ± 15.1 68.3 ± 16.2* 
BP <130/80 mmHg (%)  60.2 52.0 40.5 29.0 19.1* 
Antihypertensives (%)  4.4 10.8 31.0 52.0 66.5* 
Hypertension (%)  12.8 20.2 41.8 65.8 81.9* 
BMI (kg/m2 24.8 ± 4.3 25.4 ± 3.8 25.5 ± 3.7 25.4 ± 3.9 25.0 ± 3.8* 
Total cholesterol (mmol/l) 11,855 4.49 ± 0.89 4.67 ± 0.91 4.80 ± 0.91 4.93 ± 0.92 4.91 ± 0.88* 
Triglycerides (mmol/l) 11,358 1.12 ± 1.01 1.12 ± 0.90 1.11 ± 0.71 1.15 ± 0.78 1.13 ± 0.66 
HDL cholesterol (mmol/l) 11,219 1.47 ± 0.46 1.53 ± 0.45 1.61 ± 0.47 1.68 ± 0.53 1.74 ± 0.53* 
LDL cholesterol (mmol/l) 10,993 2.53 ± 0.76 2.64 ± 0.80 2.71 ± 0.78 2.74 ± 0.79 2.68 ± 0.76* 
Lipid-lowering drugs (%) 13,091 3.0 8.5 20.9 36.2 50.8* 
Smokers (%) 10,832 12.8 14.2 13.4 14.3 11.1 
ASA (%) 11,980 0.7 2.6 10.0 25.4 44.4* 

Data are mean values ± SD and frequencies. Significance levels for trend of mean values (ANOVA) or frequencies (χ2 test):

*

P < 0.001;

P > 0.05 (NS);

P < 0.05. ASA, aspirin; BP, blood pressure.

Close Modal

or Create an Account

Close Modal
Close Modal