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Table 1—

Characteristics of participants at study entry

CharacteristicsTotal
n 247 
Age (years) 11.1 ± 1.7 
Height (m) 1.49 ± 0.1 
Weight (kg) 64.3 ± 20.2 
BMI (kg/m228.3 ± 5.7 
BMI percentile 97.2 ± 3.0 
Total body fat (kg) 25.0 ± 10.5 
Total lean body mass (kg) 36.8 ± 10.2 
Tanner stage (%)  
    1 42 
    2 29 
    3 
    4 12 
    5 
Maternal gestational diabetes 53 (22) 
Family history of type 2 diabetes (%)  
    Mother 40 
    Father 48 
    Maternal grandmother 49 
    Maternal grandfather 29 
    Paternal grandmother 30 
    Paternal grandfather 22 
Insulin dynamics  
    SI (× 10−4 min−1/[μU/ml]) 1.5 (0.8–2.9) 
    AIR (μU/ml) 1,438.8 (745.1–2,778.4) 
    DI (× 10−4 min−12,213.1 (1,386.1–3,533.5) 
    Fasting glucose (mg/dl) 92.0 (85.8–98.6) 
    2-h glucose (mg/dl) 124.3 (106.9–144.5) 
CharacteristicsTotal
n 247 
Age (years) 11.1 ± 1.7 
Height (m) 1.49 ± 0.1 
Weight (kg) 64.3 ± 20.2 
BMI (kg/m228.3 ± 5.7 
BMI percentile 97.2 ± 3.0 
Total body fat (kg) 25.0 ± 10.5 
Total lean body mass (kg) 36.8 ± 10.2 
Tanner stage (%)  
    1 42 
    2 29 
    3 
    4 12 
    5 
Maternal gestational diabetes 53 (22) 
Family history of type 2 diabetes (%)  
    Mother 40 
    Father 48 
    Maternal grandmother 49 
    Maternal grandfather 29 
    Paternal grandmother 30 
    Paternal grandfather 22 
Insulin dynamics  
    SI (× 10−4 min−1/[μU/ml]) 1.5 (0.8–2.9) 
    AIR (μU/ml) 1,438.8 (745.1–2,778.4) 
    DI (× 10−4 min−12,213.1 (1,386.1–3,533.5) 
    Fasting glucose (mg/dl) 92.0 (85.8–98.6) 
    2-h glucose (mg/dl) 124.3 (106.9–144.5) 

Data are means ± SD, n (%), or geometric means (upper and lower limit SD). AIR, acute insulin response to glucose; DI, disposition index.

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