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Table 2—

Treatment recommendation for individuals with IFG, IGT, or both

PopulationTreatment
IFG or IGT Lifestyle modification (i.e., 5–10% weight loss and moderate intensity physical activity ∼30 min/day) 
Individuals with IFG and IGT and any of the following:
  • <60 years of age

  • BMI ≥35 kg/m2

  • Family history of diabetes in first-degree relatives

  • Elevated triglycerides

  • Reduced HDL cholesterol

  • Hypertension

  • A1C >6.0%

 
Lifestyle modification (as above) and/or metformin* 
PopulationTreatment
IFG or IGT Lifestyle modification (i.e., 5–10% weight loss and moderate intensity physical activity ∼30 min/day) 
Individuals with IFG and IGT and any of the following:
  • <60 years of age

  • BMI ≥35 kg/m2

  • Family history of diabetes in first-degree relatives

  • Elevated triglycerides

  • Reduced HDL cholesterol

  • Hypertension

  • A1C >6.0%

 
Lifestyle modification (as above) and/or metformin* 
*

Metformin 850 mg twice per day.

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