AUC and mean plasma insulin, AUC and mean plasma glucose, AUC Rameal, fractional glucose appearance, and time taken for 25, 50, and 75% appearance on basal insulin (IB) and prandial insulin (IP) study days
| . | IB . | IP . | P . |
|---|---|---|---|
| AUC insulin (nmol/l per 300 min) | 18.6 ± 5.1 | 34.1 ± 3.8 | 0.030 |
| Mean insulin (pmol/l) | 66 ± 15 | 119 ± 16 | 0.030 |
| AUC glucose (mmol/l per 300 min) | 3,351 ± 104 | 2,625 ± 124 | 0.004 |
| Mean glucose (mmol/l) | 10.9 ± 0.3 | 8.2 ± 0.6 | 0.004 |
| AUC Rameal (μmol/kg) | 3,307 ± 343 | 3,398 ± 197 | NS |
| Fractional appearance (%) | 73 ± 8 | 75 ± 4 | NS |
| Time taken for glucose appearance (min) | |||
| 25% dose | 31.7 ± 3.5 | 33.1 ± 3.3 | NS |
| 50% dose | 54.1 ± 4.7 | 54.6 ± 3.5 | NS |
| 75% dose | 82.8 ± 5.8 | 82.9 ± 7.1 | NS |
| . | IB . | IP . | P . |
|---|---|---|---|
| AUC insulin (nmol/l per 300 min) | 18.6 ± 5.1 | 34.1 ± 3.8 | 0.030 |
| Mean insulin (pmol/l) | 66 ± 15 | 119 ± 16 | 0.030 |
| AUC glucose (mmol/l per 300 min) | 3,351 ± 104 | 2,625 ± 124 | 0.004 |
| Mean glucose (mmol/l) | 10.9 ± 0.3 | 8.2 ± 0.6 | 0.004 |
| AUC Rameal (μmol/kg) | 3,307 ± 343 | 3,398 ± 197 | NS |
| Fractional appearance (%) | 73 ± 8 | 75 ± 4 | NS |
| Time taken for glucose appearance (min) | |||
| 25% dose | 31.7 ± 3.5 | 33.1 ± 3.3 | NS |
| 50% dose | 54.1 ± 4.7 | 54.6 ± 3.5 | NS |
| 75% dose | 82.8 ± 5.8 | 82.9 ± 7.1 | NS |