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Table 1—

AUC and mean plasma insulin, AUC and mean plasma glucose, AUC Rameal, fractional glucose appearance, and time taken for 25, 50, and 75% appearance on basal insulin (IB) and prandial insulin (IP) study days

IBIPP
AUC insulin (nmol/l per 300 min) 18.6 ± 5.1 34.1 ± 3.8 0.030 
Mean insulin (pmol/l) 66 ± 15 119 ± 16 0.030 
AUC glucose (mmol/l per 300 min) 3,351 ± 104 2,625 ± 124 0.004 
Mean glucose (mmol/l) 10.9 ± 0.3 8.2 ± 0.6 0.004 
AUC Rameal (μmol/kg) 3,307 ± 343 3,398 ± 197 NS 
Fractional appearance (%) 73 ± 8 75 ± 4 NS 
Time taken for glucose appearance (min)    
    25% dose 31.7 ± 3.5 33.1 ± 3.3 NS 
    50% dose 54.1 ± 4.7 54.6 ± 3.5 NS 
    75% dose 82.8 ± 5.8 82.9 ± 7.1 NS 
IBIPP
AUC insulin (nmol/l per 300 min) 18.6 ± 5.1 34.1 ± 3.8 0.030 
Mean insulin (pmol/l) 66 ± 15 119 ± 16 0.030 
AUC glucose (mmol/l per 300 min) 3,351 ± 104 2,625 ± 124 0.004 
Mean glucose (mmol/l) 10.9 ± 0.3 8.2 ± 0.6 0.004 
AUC Rameal (μmol/kg) 3,307 ± 343 3,398 ± 197 NS 
Fractional appearance (%) 73 ± 8 75 ± 4 NS 
Time taken for glucose appearance (min)    
    25% dose 31.7 ± 3.5 33.1 ± 3.3 NS 
    50% dose 54.1 ± 4.7 54.6 ± 3.5 NS 
    75% dose 82.8 ± 5.8 82.9 ± 7.1 NS 
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