Characteristics and fertility of the women who were first hospitalized for type 1 diabetes at age ≤16 years, 1965–2004, Sweden
| Patient characteristics . | Total . | Calendar year at first hospitalization for type 1 diabetes before 1985 . | Calendar year at first hospitalization for type 1 diabetes during or after 1985 . |
|---|---|---|---|
| n | 5,978 | 2,773 | 3,205 |
| Calendar year at entry | 1990 | 1983 | 1997 |
| Follow-up duration (years) | 13.3 ± 8.9 | 20.5 ± 6.6 | 7.1 ± 5.1 |
| Person-years accumulated | 79,774 | 56,888 | 22,886 |
| Percentage of women ever experiencing (%) | |||
| Retinopathy* | 18.7 | 34.4 | 5.2 |
| Diabetic nephropathy† | 7.9 | 14.8 | 1.9 |
| Neuropathy‡ | 5.1 | 9.4 | 1.4 |
| Cardiovascular complications§ | 4.0 | 7.5 | 0.9 |
| No. of live births | 4,013 | 31,24 | 889 |
| Age at first delivery (years) | 25.8 | 26.3 | 24.2 |
| Patient characteristics . | Total . | Calendar year at first hospitalization for type 1 diabetes before 1985 . | Calendar year at first hospitalization for type 1 diabetes during or after 1985 . |
|---|---|---|---|
| n | 5,978 | 2,773 | 3,205 |
| Calendar year at entry | 1990 | 1983 | 1997 |
| Follow-up duration (years) | 13.3 ± 8.9 | 20.5 ± 6.6 | 7.1 ± 5.1 |
| Person-years accumulated | 79,774 | 56,888 | 22,886 |
| Percentage of women ever experiencing (%) | |||
| Retinopathy* | 18.7 | 34.4 | 5.2 |
| Diabetic nephropathy† | 7.9 | 14.8 | 1.9 |
| Neuropathy‡ | 5.1 | 9.4 | 1.4 |
| Cardiovascular complications§ | 4.0 | 7.5 | 0.9 |
| No. of live births | 4,013 | 31,24 | 889 |
| Age at first delivery (years) | 25.8 | 26.3 | 24.2 |
Data are means or means ± SD unless otherwise indicated.
Retinopathy defined by ICD-7 codes 260.20, 260.21, and 260.29; ICD-8 codes 250.01, 250.02, and 250.03; ICD-9 codes 250E; and ICD-10 codes E10.3, E11.3, E12.3, E13.3, and E14.3. It included aneurysm, inter-retinal edema, intraocular pathologic neovascularization, simplex retinopathy, and proliferative retinopathy.
Diabetic nephropathy defined by ICD-7 code 260.30; ICD-8 code 250.40; ICD-9 code 250D; and ICD-10 codes E10.2, E11.2, E12.2, E13.2, and E14.2. It included persistent proteinuria, from microalbuminuria progressing to albuminuria; reduced glomerular filtration rate; and end-stage renal disease.
Neuropathy defined by ICD-7 codes 260.40 and 260.49; ICD-8 code 250.05; ICD-9 code 250F; and ICD-10 codes E10.4, E11.4, E12.4, E13.4, and E14.4. It included third nerve palsy, mononeuropathy, mononeuropathy multiplex, diabetic amyotrophy, a painful polyneuropathy, autonomic neuropathy, thoracoabdominal neuropathy, and unspecified diabetic neuropathy.
Including ischemic heart diseases defined by ICD-7 code 420, ICD-8 codes 410–414, ICD-9 codes 410–414, and ICD-10 codes I20–I25; diseases of arteries, arterioles, and capillaries defined by ICD-7 codes 450–456, ICD-8 codes 440–448, ICD-9 codes 440–448, and ICD-10 codes I70–I79, I98.8, and I99; and surgery for cardiovascular diseases (Swedish codes for surgical procedures 8800–8839 and 8861–8869 before 1997 and PA–PG for 1997 and thereafter).