Skip to Main Content
Table 1—

Clinical characteristics of subjects with resistant hypertension with and without primary aldosteronism

VariablesAll subjectsNo primary aldosteronismPrimary aldosteronism
n 100 86 14 
Age (years) 59 ± 9 60 ± 9 57 ± 6 
Race    
    Black (%) 93 (93) 80 (93) 13 (93) 
    Caucasian/Hispanic/other 5/1/1 4/1/1 1/0/0 
BMI (kg/m234.4 ± 8 34.5 ± 8 34.2 ± 8 
Duration of diabetes (years) 8.9 ± 7 8.7 ± 7 9.8 ± 8 
Duration of hypertension (years) 16 ± 12 16 ± 12 15 ± 7 
Systolic BP (mmHg) 157 ± 16 158 ± 17 157 ± 15 
Diastolic BP (mmHg) 90 ± 9 89 ± 8 93 ± 10 
Number of BP drugs 3.7 ± 1 3.7 ± 1 3.6 ± 1 
Subjects taking a BP agent    
    ACE inhibitor or ARB 96 (98) 83 (99) 13 (93) 
    Diuretic 90 (92) 77 (92) 13 (93) 
    β-Blocker 72 (74) 61 (73) 11 (79) 
    Calcium channel blocker 61 (62) 52 (62) 9 (64) 
    Other 30 (31) 26 (31) 4 (29) 
Potassium (mEq/l) 4 ± 0.4 4 ± 0.4* 3.7 ± 0.4* 
Creatinine (mg/dl) 1.0 ± 0.2 1.0 ± 0.2* 0.9 ± 0.2* 
A1C (%) 7.1 ± 1.4 7.1 ± 1.4 6.9 ± 1.1 
PAC (ng/dl) 10 ± 7 9.1 ± 6 15.6 ± 8 
PRA (ng/ml) 4.8 ± 11 5.5 ± 12 0.2 ± 0.1 
PAC-to-PRA ratio (ng · ml−1 · h−133 ± 47 21 ± 30 98 ± 74 
VariablesAll subjectsNo primary aldosteronismPrimary aldosteronism
n 100 86 14 
Age (years) 59 ± 9 60 ± 9 57 ± 6 
Race    
    Black (%) 93 (93) 80 (93) 13 (93) 
    Caucasian/Hispanic/other 5/1/1 4/1/1 1/0/0 
BMI (kg/m234.4 ± 8 34.5 ± 8 34.2 ± 8 
Duration of diabetes (years) 8.9 ± 7 8.7 ± 7 9.8 ± 8 
Duration of hypertension (years) 16 ± 12 16 ± 12 15 ± 7 
Systolic BP (mmHg) 157 ± 16 158 ± 17 157 ± 15 
Diastolic BP (mmHg) 90 ± 9 89 ± 8 93 ± 10 
Number of BP drugs 3.7 ± 1 3.7 ± 1 3.6 ± 1 
Subjects taking a BP agent    
    ACE inhibitor or ARB 96 (98) 83 (99) 13 (93) 
    Diuretic 90 (92) 77 (92) 13 (93) 
    β-Blocker 72 (74) 61 (73) 11 (79) 
    Calcium channel blocker 61 (62) 52 (62) 9 (64) 
    Other 30 (31) 26 (31) 4 (29) 
Potassium (mEq/l) 4 ± 0.4 4 ± 0.4* 3.7 ± 0.4* 
Creatinine (mg/dl) 1.0 ± 0.2 1.0 ± 0.2* 0.9 ± 0.2* 
A1C (%) 7.1 ± 1.4 7.1 ± 1.4 6.9 ± 1.1 
PAC (ng/dl) 10 ± 7 9.1 ± 6 15.6 ± 8 
PRA (ng/ml) 4.8 ± 11 5.5 ± 12 0.2 ± 0.1 
PAC-to-PRA ratio (ng · ml−1 · h−133 ± 47 21 ± 30 98 ± 74 

Data are means ± SD or n (%).

*

P < 0.05;

P < 0.001. BP, blood pressure.

Close Modal

or Create an Account

Close Modal
Close Modal