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Table 1—

Baseline characteristics of men and women studied: DESIR

MenWomen
P values
PremenopausalPostmenopausalMen and womenPre- and postmenopausal women
n 469 278 197   
Age (years) 47 ± 10 41 ± 7 57 ± 5 0.3 <0.0001 
Ferritin (μg/l) 178 ± 90 56.4 ± 40.8 91.7 ± 54.3 <0.0001 <0.0001 
    Geometric mean (μg/l) 152 45.9 76.5 <0.0001 <0.000 
Transferrin (g/l) 2.27 ± 0.30 2.33 ± 0.36 2.30 ± 0.36 0.1 0.2 
CRP (mg/l) 1.61 ± 1.43 1.75 ± 1.60 1.88 ± 1.57 0.05 0.1 
Waist circumference (cm) 89 ± 9 75 ± 9 80 ± 10 <0.0001 <0.0001 
BMI (kg/m225.4 ± 3.2 23.3 ± 3.6 24.7 ± 3.7 <0.0001 <0.0001 
Systolic blood pressure (mmHg) 132 ± 15 122 ± 15 132 ± 16 <0.0001 <0.0001 
Diastolic blood pressure (mmHg) 82 ± 10 76 ± 10 79 ± 9 <0.0001 <0.0001 
Total cholesterol (mmol/l) 5.76 ± 0.92 5.42 ± 0.86 6.01 ± 0.97 0.1 <0.0001 
HDL cholesterol (mmol/l) 1.50 ± 0.37 1.76 ± 0.42 1.87 ± 0.46 <0.0001 0.009 
Triglycerides (mmol/l) 1.18 ± 0.63 0.94 ± 0.53 0.99 ± 0.48 <0.0001 0.02 
Plasma glucose (mmol/l) 5.54 ± 0.60 5.07 ± 0.70 5.26 ± 1.08 <0.0001 0.004 
Serum insulin (pmol/l) 47.5 ± 28.2 42.8 ± 22.2 42.3 ± 21.9 0.01 0.9 
HOMA2-IR 1.05 ± 0.63 0.92 ± 0.49 0.93 ± 0.49 <0.0001 0.8 
HOMA2-%β 78 ± 29 87 ± 31 81 ± 25 <0.001 0.009 
Alcohol consumption (g/day) 23 ± 22 6.7 ± 10.3 8.6 ± 12.1 <0.0001 0.7 
ALT (U/l) 29.7 ± 16.7 17.9 ± 7.4 21.7 ± 9.1 <0.0001 <0.0001 
GGT (U/l) 39.7 ± 39.5 20.5 ± 15.8 23.0 ± 15.0 <0.0001 0.007 
Participants with medication for      
    Hypertension 48 (10.2) 18 (6.5) 36 (18.3) 0.6 <0.0001 
    Dyslipidemia 41 (8.7) 4 (1.4) 24 (12.2) 0.09 <0.0001 
    Hyperglycemia 7 (1.5) 1 (0.4) 1 (0.5) 0.9 0.9 
MenWomen
P values
PremenopausalPostmenopausalMen and womenPre- and postmenopausal women
n 469 278 197   
Age (years) 47 ± 10 41 ± 7 57 ± 5 0.3 <0.0001 
Ferritin (μg/l) 178 ± 90 56.4 ± 40.8 91.7 ± 54.3 <0.0001 <0.0001 
    Geometric mean (μg/l) 152 45.9 76.5 <0.0001 <0.000 
Transferrin (g/l) 2.27 ± 0.30 2.33 ± 0.36 2.30 ± 0.36 0.1 0.2 
CRP (mg/l) 1.61 ± 1.43 1.75 ± 1.60 1.88 ± 1.57 0.05 0.1 
Waist circumference (cm) 89 ± 9 75 ± 9 80 ± 10 <0.0001 <0.0001 
BMI (kg/m225.4 ± 3.2 23.3 ± 3.6 24.7 ± 3.7 <0.0001 <0.0001 
Systolic blood pressure (mmHg) 132 ± 15 122 ± 15 132 ± 16 <0.0001 <0.0001 
Diastolic blood pressure (mmHg) 82 ± 10 76 ± 10 79 ± 9 <0.0001 <0.0001 
Total cholesterol (mmol/l) 5.76 ± 0.92 5.42 ± 0.86 6.01 ± 0.97 0.1 <0.0001 
HDL cholesterol (mmol/l) 1.50 ± 0.37 1.76 ± 0.42 1.87 ± 0.46 <0.0001 0.009 
Triglycerides (mmol/l) 1.18 ± 0.63 0.94 ± 0.53 0.99 ± 0.48 <0.0001 0.02 
Plasma glucose (mmol/l) 5.54 ± 0.60 5.07 ± 0.70 5.26 ± 1.08 <0.0001 0.004 
Serum insulin (pmol/l) 47.5 ± 28.2 42.8 ± 22.2 42.3 ± 21.9 0.01 0.9 
HOMA2-IR 1.05 ± 0.63 0.92 ± 0.49 0.93 ± 0.49 <0.0001 0.8 
HOMA2-%β 78 ± 29 87 ± 31 81 ± 25 <0.001 0.009 
Alcohol consumption (g/day) 23 ± 22 6.7 ± 10.3 8.6 ± 12.1 <0.0001 0.7 
ALT (U/l) 29.7 ± 16.7 17.9 ± 7.4 21.7 ± 9.1 <0.0001 <0.0001 
GGT (U/l) 39.7 ± 39.5 20.5 ± 15.8 23.0 ± 15.0 <0.0001 0.007 
Participants with medication for      
    Hypertension 48 (10.2) 18 (6.5) 36 (18.3) 0.6 <0.0001 
    Dyslipidemia 41 (8.7) 4 (1.4) 24 (12.2) 0.09 <0.0001 
    Hyperglycemia 7 (1.5) 1 (0.4) 1 (0.5) 0.9 0.9 

Data are n, means ± SD, or n (%).

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