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Table 1—

Crude incidence rate and adjusted HRs (95% CIs) of cancer by diabetes status at baseline, ARIC Study, 1987–2000

No. developing cancerPerson-yearsCrude incidence rateAge-, race-, and sex-adjusted HR (95% CI)Fully adjusted HR (95% CI)*
Colorectal cancer      
    No diabetes 157 137,764 1.14 
    Diabetes 23 15,023 1.53 1.18 (0.76–1.84) 1.13 (0.71–1.84) 
Colon cancer      
    No diabetes 110 137,967 0.80  
    Diabetes 18 15,033 1.20 1.31 (0.79–2.16) 1.19 (0.70–2.03) 
Lung cancer      
    No diabetes 215 138,106 1.56 
    Diabetes 23 15,066 1.53 0.80 (0.52–1.24) 0.97 (0.62–1.51) 
Breast cancer (women)      
    No diabetes 305 75,124 4.06 
    Diabetes 36 8,023 4.49 1.07 (0.76–1.52) 1.08 (0.75–1.54) 
Prostate cancer      
    No diabetes 330 60,374 5.47 
    Diabetes 34 6,786 5.01 0.75 (0.53–1.07) 0.71 (0.49–1.03) 
No. developing cancerPerson-yearsCrude incidence rateAge-, race-, and sex-adjusted HR (95% CI)Fully adjusted HR (95% CI)*
Colorectal cancer      
    No diabetes 157 137,764 1.14 
    Diabetes 23 15,023 1.53 1.18 (0.76–1.84) 1.13 (0.71–1.84) 
Colon cancer      
    No diabetes 110 137,967 0.80  
    Diabetes 18 15,033 1.20 1.31 (0.79–2.16) 1.19 (0.70–2.03) 
Lung cancer      
    No diabetes 215 138,106 1.56 
    Diabetes 23 15,066 1.53 0.80 (0.52–1.24) 0.97 (0.62–1.51) 
Breast cancer (women)      
    No diabetes 305 75,124 4.06 
    Diabetes 36 8,023 4.49 1.07 (0.76–1.52) 1.08 (0.75–1.54) 
Prostate cancer      
    No diabetes 330 60,374 5.47 
    Diabetes 34 6,786 5.01 0.75 (0.53–1.07) 0.71 (0.49–1.03) 
*

Adjusted for baseline age (continuous), race (white or black), BMI (continuous), smoking status (current smoker or nonsmoker), pack-years (continuous), ethanol intake (continuous), sport index (continuous), education (< high school graduate or ≥ high school graduate), sex, and current hormone replacement therapy (male, female with no hormone replacement therapy, or female with hormone replacement therapy).

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