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Table 2—

Age-, race-, and sex-adjusted means and percentages of baseline risk factors by TCF7L2 genotype (rs7903146 SNP), ARIC Study, 1987–1989

TCF7L2 (rs7903146) SNP
CCCTTT
n 6,536 5,424 1,137 
Prevalences    
    Diabetes (%) 9.0 11.9* 13.7* 
    Current smoking (%) 24.6 26.0 27.9* 
    High school graduate (%) 77.7 75.2* 76.8 
    Current hormone replacement therapy use (women) (%) 23.3 22.0 20.9 
Means    
    BMI (kg/m227.8 27.6* 27.5* 
    Pack-years of smoking 309 317 336* 
    Ethanol intake (g/week) 42.1 42.3 42.9 
    Sport activity index (range 1–5) 2.44 2.44 2.42 
TCF7L2 (rs7903146) SNP
CCCTTT
n 6,536 5,424 1,137 
Prevalences    
    Diabetes (%) 9.0 11.9* 13.7* 
    Current smoking (%) 24.6 26.0 27.9* 
    High school graduate (%) 77.7 75.2* 76.8 
    Current hormone replacement therapy use (women) (%) 23.3 22.0 20.9 
Means    
    BMI (kg/m227.8 27.6* 27.5* 
    Pack-years of smoking 309 317 336* 
    Ethanol intake (g/week) 42.1 42.3 42.9 
    Sport activity index (range 1–5) 2.44 2.44 2.42 
*

P < 0.05 compared with CC.

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