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Table 1—

Baseline characteristics according to the presence of metabolic syndrome and associations between the different components of the metabolic syndrome: the 3C Study, France, 1999–2004

Total cohortMetabolic syndromeNo metabolic syndromePComponents of the metabolic syndrome
High blood pressureHigh waist circumferenceHigh triglyceridesLow HDL cholesterolHigh glycemia
n 7,087 1,121 5,966  6,064 2,049 1,247 741 816 
Age (years) 73.4 ± 4.9 73.8 ± 4.8 73.4 ± 4.9 0.05 73.7 ± 4.9 74.0 ± 4.9 73.3 ± 4.9 73.6 ± 4.9 73.2 ± 4.7 
Men (%) 39.0 41.6 38.5 0.05 40.8 32.3 45.9 35.4 39.0 
Education level (no or primary) 23.6 29.1 22.6 <0.0001 24.4 28.8 25.9 29.9 23.6 
ApoE ε4* 20.4 21.0 20.3 0.60 20.3 19.6 20.4 23.5 20.4 
High blood pressure 85.6 98.2 83.2 <0.0001 NA 91.6 90.0 88.3 95.2 
High waist circumference 28.9 78.5 19.6 <0.0001 31.0 NA 44.2 50.4 50.2 
High triglycerides§ 17.6 66.4 8.4 <0.0001 18.5 26.9 NA 50.5 32.0 
Low HDL cholesterol 10.5 47.6 3.5 <0.0001 10.8 18.3 30.2 NA 22.8 
High glycemia 11.5 47.6 4.7 <0.0001 12.9 20.0 20.9 25.0 NA 
Impaired fasting glucose without diabetes** 3.9 15.3 1.8 <0.0001 4.3 6.9 6.1 7.0 34.2 
Diabetes†† 7.6 32.3 2.9 <0.0001 8.6 13.1 14.8 18.0 65.8 
Total cohortMetabolic syndromeNo metabolic syndromePComponents of the metabolic syndrome
High blood pressureHigh waist circumferenceHigh triglyceridesLow HDL cholesterolHigh glycemia
n 7,087 1,121 5,966  6,064 2,049 1,247 741 816 
Age (years) 73.4 ± 4.9 73.8 ± 4.8 73.4 ± 4.9 0.05 73.7 ± 4.9 74.0 ± 4.9 73.3 ± 4.9 73.6 ± 4.9 73.2 ± 4.7 
Men (%) 39.0 41.6 38.5 0.05 40.8 32.3 45.9 35.4 39.0 
Education level (no or primary) 23.6 29.1 22.6 <0.0001 24.4 28.8 25.9 29.9 23.6 
ApoE ε4* 20.4 21.0 20.3 0.60 20.3 19.6 20.4 23.5 20.4 
High blood pressure 85.6 98.2 83.2 <0.0001 NA 91.6 90.0 88.3 95.2 
High waist circumference 28.9 78.5 19.6 <0.0001 31.0 NA 44.2 50.4 50.2 
High triglycerides§ 17.6 66.4 8.4 <0.0001 18.5 26.9 NA 50.5 32.0 
Low HDL cholesterol 10.5 47.6 3.5 <0.0001 10.8 18.3 30.2 NA 22.8 
High glycemia 11.5 47.6 4.7 <0.0001 12.9 20.0 20.9 25.0 NA 
Impaired fasting glucose without diabetes** 3.9 15.3 1.8 <0.0001 4.3 6.9 6.1 7.0 34.2 
Diabetes†† 7.6 32.3 2.9 <0.0001 8.6 13.1 14.8 18.0 65.8 

Data are means ± SD or percent. Metabolic syndrome was defined by the NCEP ATP III criteria.

*

ApoE ε4: presence of at least one allele ε4 in apoE genotype.

Systolic blood pressure >130 mmHg or diastolic blood pressure >85 mmHg or medication.

Waist circumference >88 cm in women or >102 cm in men.

§

Triglycerides ≥150 mg/dl.

HDL cholesterol <50 mg/dl in women or <40 mg/dl in men.

Fasting glycemia ≥110 mg/dl or nonfasting glycemia ≥200 mg/dl or antidiabetes medication.

**

Impaired fasting glucose ≥110 mg/dl without diabetes.

††

Diabetes: fasting glycemia ≥126 mg/dl or nonfasting glycemia ≥200 mg/dl or antidiabetes medication. P value: Student and Pearson χ2 tests used for continuous and categorical variables, respectively, to compare baseline characteristics between subjects with metabolic syndrome and those without. NA, nonapplicable.

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