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Table 3—

HR (95% CI) for death from stroke corresponding to a 1-SD increase in FPG or 2-h plasma glucose levels fitted in the model separately

Adjustment*MenWomenTotal
n  11,120 9,390 20,510 
Model 1 Age, study, BMI, total cholesterol    
    FPG  1.04 (0.85–1.27) 1.54 (1.26–1.90) 1.18 (1.03–1.35) 
    2-h plasma glucose  1.21 (1.06–1.38) 1.31 (1.07–1.61) 1.25 (1.12–1.40) 
Model 2 Model 1 + smoking    
    FPG  1.04 (0.86–1.27) 1.56 (1.26–1.92) 1.27 (1.14–1.42) 
    2-h plasma glucose  1.23 (1.08–1.40) 1.34 (1.09–1.65) 1.18 (1.03–1.36) 
Model 3 Model 2 + hypertension    
    FPG  1.02 (0.83–1.25) 1.52 (1.22–1.88) 1.16 (1.00–1.33) 
    2-h plasma glucose  1.21 (1.06–1.38) 1.31 (1.06–1.61) 1.25 (1.12–1.40) 
χ2 for FPG, 1 df (P 3.29 (0.07) 4.08 (0.04) 0.57 (0.45) 
χ2 for 2-h PG, 1 df (P 10.12 (0.001) 0.01 (0.94) 10.45 (0.001) 
Adjustment*MenWomenTotal
n  11,120 9,390 20,510 
Model 1 Age, study, BMI, total cholesterol    
    FPG  1.04 (0.85–1.27) 1.54 (1.26–1.90) 1.18 (1.03–1.35) 
    2-h plasma glucose  1.21 (1.06–1.38) 1.31 (1.07–1.61) 1.25 (1.12–1.40) 
Model 2 Model 1 + smoking    
    FPG  1.04 (0.86–1.27) 1.56 (1.26–1.92) 1.27 (1.14–1.42) 
    2-h plasma glucose  1.23 (1.08–1.40) 1.34 (1.09–1.65) 1.18 (1.03–1.36) 
Model 3 Model 2 + hypertension    
    FPG  1.02 (0.83–1.25) 1.52 (1.22–1.88) 1.16 (1.00–1.33) 
    2-h plasma glucose  1.21 (1.06–1.38) 1.31 (1.06–1.61) 1.25 (1.12–1.40) 
χ2 for FPG, 1 df (P 3.29 (0.07) 4.08 (0.04) 0.57 (0.45) 
χ2 for 2-h PG, 1 df (P 10.12 (0.001) 0.01 (0.94) 10.45 (0.001) 

χ2 indicates the changes in the model prediction when FPG or 2-hPG was removed from the model where both were fitted simultaneously. Subjects with diagnosed diabetes were excluded.

*

Adjusted for sex when men and women are combined.

SD = 1.3 for FPG and SD = 2.7 for 2-h plasma glucose.

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