Cardiovascular autonomic tests and suggested indications for their use
| . | Clinical diagnosis . | Research . | End point in clinical trials . |
|---|---|---|---|
| HR cardiovascular tests | Yes | Yes | Yes |
| Orthostatic hypotension test | Yes | Yes | No (low sensitivity) |
| QT interval | Yes (additional information and risk stratification) | Yes | No (low sensitivity) |
| ABPM for dipping status | Yes (risk stratification) | Yes | No (low sensitivity) |
| HRV time- and frequency-domain indices | Yes (early additional information and risk stratification) | Yes | Yes |
| BRS measures | No (offers early additional information and risk stratification but low availability) | Yes | Yes |
| Scintigraphic studies | No (low availability and limited standardization) | Yes | Yes |
| MNSA | No (low availability and limited data in CAN) | Yes | Possible (used in lifestyle intervention trials in obesity) |
| Catecholamine assessment | No (low availability) | Yes | Possible (used in lifestyle intervention trials in obesity) |
| . | Clinical diagnosis . | Research . | End point in clinical trials . |
|---|---|---|---|
| HR cardiovascular tests | Yes | Yes | Yes |
| Orthostatic hypotension test | Yes | Yes | No (low sensitivity) |
| QT interval | Yes (additional information and risk stratification) | Yes | No (low sensitivity) |
| ABPM for dipping status | Yes (risk stratification) | Yes | No (low sensitivity) |
| HRV time- and frequency-domain indices | Yes (early additional information and risk stratification) | Yes | Yes |
| BRS measures | No (offers early additional information and risk stratification but low availability) | Yes | Yes |
| Scintigraphic studies | No (low availability and limited standardization) | Yes | Yes |
| MNSA | No (low availability and limited data in CAN) | Yes | Possible (used in lifestyle intervention trials in obesity) |
| Catecholamine assessment | No (low availability) | Yes | Possible (used in lifestyle intervention trials in obesity) |
ABPM, ambulatory BP monitoring; HRV, heart rate variability; MNSA, muscle sympathetic nerve activity.