Skip to Main Content
Table 2

Prevalence of clinical (symptoms and signs) and NCS results suggestive of distal symmetrical polyneuropathy at DCCT baseline, DCCT closeout, and EDIC years 13–14

VariableDCCT baselineDCCT closeoutEDIC years 13–14
Clinical examination    
    Symptoms    
        INT 32 (5) 44 (7)* 119 (20) 
        CONV 39 (7) 75 (13) 172 (30) 
    Abnormal sensation    
        INT 128 (21) 147 (25) 248 (41)* 
        CONV 120 (21) 206 (36) 292 (50) 
    Abnormal reflexes    
        INT 105 (18) 135 (23) 264 (44) 
        CONV 93 (16) 212 (37) 292 (50) 
    Clinical neuropathy    
        INT 57 (10) 88 (15) 204 (34) 
        CONV 48 (8) 128 (22) 240 (41) 
Electrophysiology    
    Abnormal NCS    
        INT 185 (31) 164 (28) 326 (54) 
        CONV 196 (34) 288 (50) 401 (69) 
Primary outcome    
    Confirmed clinical neuropathy    
        INT 39 (7) 52 (9) 152 (25) 
        CONV 31 (5) 97 (17) 204 (35) 
VariableDCCT baselineDCCT closeoutEDIC years 13–14
Clinical examination    
    Symptoms    
        INT 32 (5) 44 (7)* 119 (20) 
        CONV 39 (7) 75 (13) 172 (30) 
    Abnormal sensation    
        INT 128 (21) 147 (25) 248 (41)* 
        CONV 120 (21) 206 (36) 292 (50) 
    Abnormal reflexes    
        INT 105 (18) 135 (23) 264 (44) 
        CONV 93 (16) 212 (37) 292 (50) 
    Clinical neuropathy    
        INT 57 (10) 88 (15) 204 (34) 
        CONV 48 (8) 128 (22) 240 (41) 
Electrophysiology    
    Abnormal NCS    
        INT 185 (31) 164 (28) 326 (54) 
        CONV 196 (34) 288 (50) 401 (69) 
Primary outcome    
    Confirmed clinical neuropathy    
        INT 39 (7) 52 (9) 152 (25) 
        CONV 31 (5) 97 (17) 204 (35) 

Data are n (%).

*P < 0.01 former intensive treatment group (INT) vs. former conventional treatment group (CONV).

P < 0.001 INT vs. CONV.

Close Modal

or Create an Account

Close Modal
Close Modal