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Table 3

Regression modeling: small fiber neuropathy by ethnicity

Risk of small fiber neuropathy in Indian Asians vs. Europeans with adjustment for covariates
Adjustment factorsOdds ratio (95% CI)P value*
Unadjusted 0.61 (0.39–0.95) 0.03 
Age + diabetes duration 0.58 (0.37–0.93) 0.02 
Age + duration + pack-years smoked 0.58 (0.35–1.00) 0.04 
Age + duration + pack-years smoked + height 0.61 (0.36–1.02) 0.06 
Age + duration + pack-years smoked + ABPI <0.85 0.64 (0.38–1.08) 0.09 
Age + duration + pack-years smoked + TCpO2 0.63 (0.37–1.08) 0.09 
Multivariate model: age + duration + pack-years smoked + height + ABPI <0.85 + TCpO2 0.70 (0.40–1.21) 0.2 
Risk of small fiber neuropathy in Indian Asians vs. Europeans with adjustment for covariates
Adjustment factorsOdds ratio (95% CI)P value*
Unadjusted 0.61 (0.39–0.95) 0.03 
Age + diabetes duration 0.58 (0.37–0.93) 0.02 
Age + duration + pack-years smoked 0.58 (0.35–1.00) 0.04 
Age + duration + pack-years smoked + height 0.61 (0.36–1.02) 0.06 
Age + duration + pack-years smoked + ABPI <0.85 0.64 (0.38–1.08) 0.09 
Age + duration + pack-years smoked + TCpO2 0.63 (0.37–1.08) 0.09 
Multivariate model: age + duration + pack-years smoked + height + ABPI <0.85 + TCpO2 0.70 (0.40–1.21) 0.2 
Autonomic nerve function (heart rate decline in response to deep breathing, bpm) by ethnicity
Adjustment factorsOdds ratio (95% CI)
P value*
Indian AsianEuropean
Unadjusted 10.8 (9.8–11.8) 8.5 (7.5–9.5) 0.002 
Age + diabetes duration 10.8 (9.8–11.7) 8.7 (7.8–9.6) 0.003 
Age + duration + height 10.9 (9.9–11.8) 8.6 (7.7–9.6) 0.002 
Age + duration + weight 10.4 (9.4,11.4) 9.0 (8.0–10.0) 0.07 
Age + duration + BMI 10.4 (9.4–11.3) 9.1 (8.1–10.0) 0.08 
Autonomic nerve function (heart rate decline in response to deep breathing, bpm) by ethnicity
Adjustment factorsOdds ratio (95% CI)
P value*
Indian AsianEuropean
Unadjusted 10.8 (9.8–11.8) 8.5 (7.5–9.5) 0.002 
Age + diabetes duration 10.8 (9.8–11.7) 8.7 (7.8–9.6) 0.003 
Age + duration + height 10.9 (9.9–11.8) 8.6 (7.7–9.6) 0.002 
Age + duration + weight 10.4 (9.4,11.4) 9.0 (8.0–10.0) 0.07 
Age + duration + BMI 10.4 (9.4–11.3) 9.1 (8.1–10.0) 0.08 

*P value for ethnic difference.

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