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Table 2

LGA (birth weight ≥90th percentile for gestational age), overweight, and obesity (BMI Z scores ≥85th and 95th percentiles, respectively) at age 2 years according to strata of maternal OGTT glucose at 24–32 weeks of gestation

LGA (birth)Overweight (age 2 years)Obesity (age 2 years)
Fasting glucose    
    <75 mg/dl 2/68 (2.9) 17/66 (25.8) 11/66 (16.7) 
    75–79 mg/dl 14/308 (4.5) 105/296 (35.5) 50/296 (16.9) 
    80–84 mg/dl 26/394 (6.6) 134/386 (34.7) 55/386 (14.2) 
    85–89 mg/dl 27/230 (11.7) 81/229 (35.4) 36/229 (15.7) 
    90–94 mg/dl 13/125 (10.4) 51/125 (40.8) 29/125 (23.2) 
    ≥95 mg/dl 11/40 (27.5) 14/39 (35.9) 9/39 (23.1) 
    Ptrend <0.001 0.16 0.16 
1-h glucose    
    <106 mg/dl 8/176 (4.5) 50/171 (29.2) 24/171 (14.0) 
    106–132 mg/dl 17/388 (4.4) 123/382 (32.2) 58/382 (15.2) 
    133–155 mg/dl 34/332 (10.2) 127/324 (39.2) 61/324 (18.8) 
    156–171 mg/dl 16/156 (10.3) 58/153 (37.9) 30/153 (19.6) 
    172–193 mg/dl 12/83 (14.5) 32/81 (39.5) 11/81 (13.6) 
    ≥194 mg/dl 6/30 (20.0) 12/30 (40.0) 6/30 (20.0) 
    Ptrend <0.001 0.017 0.27 
2-h glucose    
    <91 mg/dl 10/187 (5.3) 54/183 (29.5) 26/183 (14.2) 
    91–108 mg/dl 28/455 (6.2) 156/445 (35.1) 75/445 (16.9) 
    109–125 mg/dl 23/299 (7.7) 105/293 (35.8) 49/293 (16.7) 
    126–139 mg/dl 17/129 (13.2) 52/127 (40.9) 26/127 (20.5) 
    140–157 mg/dl 6/67 (9.0) 23/65 (35.4) 9/65 (13.8) 
    ≥158 mg/dl 9/28 (32.1) 12/28 (42.9) 5/28 (17.9) 
    Ptrend <0.001 0.06 0.49 
Area under the curve for glucose    
    <196 mg/dl · h 11/200 (5.5) 59/195 (30.3) 31/195 (15.9) 
    196–228 mg/dl · h 17/389 (4.4) 132/381 (34.6) 57/381 (15.0) 
    229–256 mg/dl · h 29/308 (9.4) 109/302 (36.1) 52/302 (17.2) 
    257–276 mg/dl · h 15/137 (10.9) 54/135 (40.0) 28/135 (20.7) 
    277–303 mg/dl · h 12/96 (12.5) 35/93 (37.6) 17/93 (18.3) 
    ≥304 mg/dl · h 9/35 (25.7) 13/35 (37.1) 5/35 (14.3) 
    Ptrend <0.001 0.10 0.34 
LGA (birth)Overweight (age 2 years)Obesity (age 2 years)
Fasting glucose    
    <75 mg/dl 2/68 (2.9) 17/66 (25.8) 11/66 (16.7) 
    75–79 mg/dl 14/308 (4.5) 105/296 (35.5) 50/296 (16.9) 
    80–84 mg/dl 26/394 (6.6) 134/386 (34.7) 55/386 (14.2) 
    85–89 mg/dl 27/230 (11.7) 81/229 (35.4) 36/229 (15.7) 
    90–94 mg/dl 13/125 (10.4) 51/125 (40.8) 29/125 (23.2) 
    ≥95 mg/dl 11/40 (27.5) 14/39 (35.9) 9/39 (23.1) 
    Ptrend <0.001 0.16 0.16 
1-h glucose    
    <106 mg/dl 8/176 (4.5) 50/171 (29.2) 24/171 (14.0) 
    106–132 mg/dl 17/388 (4.4) 123/382 (32.2) 58/382 (15.2) 
    133–155 mg/dl 34/332 (10.2) 127/324 (39.2) 61/324 (18.8) 
    156–171 mg/dl 16/156 (10.3) 58/153 (37.9) 30/153 (19.6) 
    172–193 mg/dl 12/83 (14.5) 32/81 (39.5) 11/81 (13.6) 
    ≥194 mg/dl 6/30 (20.0) 12/30 (40.0) 6/30 (20.0) 
    Ptrend <0.001 0.017 0.27 
2-h glucose    
    <91 mg/dl 10/187 (5.3) 54/183 (29.5) 26/183 (14.2) 
    91–108 mg/dl 28/455 (6.2) 156/445 (35.1) 75/445 (16.9) 
    109–125 mg/dl 23/299 (7.7) 105/293 (35.8) 49/293 (16.7) 
    126–139 mg/dl 17/129 (13.2) 52/127 (40.9) 26/127 (20.5) 
    140–157 mg/dl 6/67 (9.0) 23/65 (35.4) 9/65 (13.8) 
    ≥158 mg/dl 9/28 (32.1) 12/28 (42.9) 5/28 (17.9) 
    Ptrend <0.001 0.06 0.49 
Area under the curve for glucose    
    <196 mg/dl · h 11/200 (5.5) 59/195 (30.3) 31/195 (15.9) 
    196–228 mg/dl · h 17/389 (4.4) 132/381 (34.6) 57/381 (15.0) 
    229–256 mg/dl · h 29/308 (9.4) 109/302 (36.1) 52/302 (17.2) 
    257–276 mg/dl · h 15/137 (10.9) 54/135 (40.0) 28/135 (20.7) 
    277–303 mg/dl · h 12/96 (12.5) 35/93 (37.6) 17/93 (18.3) 
    ≥304 mg/dl · h 9/35 (25.7) 13/35 (37.1) 5/35 (14.3) 
    Ptrend <0.001 0.10 0.34 

Data are n/total n (%). LGA, large for gestational age.

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