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Table 2

Physical, clinical, and fasting laboratory findings by diabetes antibody status at the screening assessment

nAntibody-negativenAntibody-positiveP value
n  1,088  118  
BMI 1,082 34.9 (30.3, 39.9) 115 29.1 (25.4, 35.2) <0.0001 
BMI z score 1,082 2.3 (2.1, 2.6) 115 1.9 (1.5, 2.4) <0.0001 
Systolic blood pressure 1,075 115.0 (107.7, 123.3) 114 110.5 (103.7, 115.7) <0.0001 
Diastolic blood pressure 1,075 68.3 (63.3, 74.3) 114 64.7 (60.3, 70.0) <0.0001 
Acanthosis nigricans (%) 1,032 84.4 108 67.8 <0.0001 
Insulin use (%) 1,088 38.8 118 54.2 0.0013 
Metformin use (%) 1,088 73.8 117 62.7 0.0155 
A1C (normal = 3.9–6.1%) 1,082 6.9 (6.0, 8.8) 117 7.6 (6.2, 10.1) 0.0111 
Fasting C-peptide (normal = 0.5–3.0 ng/ml) 1,088 3.8 (2.6, 5.2) 118 2.0 (1.2, 2.7) <0.0001 
Total cholesterol 1,086 156 (135, 179) 118 151 (133, 173) 0.1156 
LDL cholesterol 1,085 92 (74, 111) 117 87 (74, 101) 0.1351 
HDL cholesterol 1,085 39 (33, 46) 117 43 (37, 51) <0.0001 
Triglycerides 1,086 106.5 (73, 156) 118 77 (56, 120) <0.0001 
nAntibody-negativenAntibody-positiveP value
n  1,088  118  
BMI 1,082 34.9 (30.3, 39.9) 115 29.1 (25.4, 35.2) <0.0001 
BMI z score 1,082 2.3 (2.1, 2.6) 115 1.9 (1.5, 2.4) <0.0001 
Systolic blood pressure 1,075 115.0 (107.7, 123.3) 114 110.5 (103.7, 115.7) <0.0001 
Diastolic blood pressure 1,075 68.3 (63.3, 74.3) 114 64.7 (60.3, 70.0) <0.0001 
Acanthosis nigricans (%) 1,032 84.4 108 67.8 <0.0001 
Insulin use (%) 1,088 38.8 118 54.2 0.0013 
Metformin use (%) 1,088 73.8 117 62.7 0.0155 
A1C (normal = 3.9–6.1%) 1,082 6.9 (6.0, 8.8) 117 7.6 (6.2, 10.1) 0.0111 
Fasting C-peptide (normal = 0.5–3.0 ng/ml) 1,088 3.8 (2.6, 5.2) 118 2.0 (1.2, 2.7) <0.0001 
Total cholesterol 1,086 156 (135, 179) 118 151 (133, 173) 0.1156 
LDL cholesterol 1,085 92 (74, 111) 117 87 (74, 101) 0.1351 
HDL cholesterol 1,085 39 (33, 46) 117 43 (37, 51) <0.0001 
Triglycerides 1,086 106.5 (73, 156) 118 77 (56, 120) <0.0001 

Data are % or median (25th, 75th percentile).

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