Characteristics of the case subjects and control subjects in this study
| . | Case subjects . | Control subjects . |
|---|---|---|
| n | 27 | 53 |
| Age at onset of islet autoimmunity (months)* | 12.1 (5–37) | 12.3 (5–37) |
| Female sex | 17 (63) | 23 (43) |
| No. of other children in the family (siblings, half-siblings, step siblings) | ||
| None | 5 (18.5) | 16 (30.2) |
| ≥1 | 22 (81.5) | 37 (69.8) |
| First-degree relative with diabetes | ||
| None | 17 (63) | 50 (94.3) |
| Yes, of that | 10 (37) | 3 (5.7) |
| Sibling only | 3 | 0 |
| Father only | 3 | 2 |
| Mother only | 2 | 1 |
| Multiple family members | 2 | 0 |
| Progression from islet autoimmunity to type 1 diabetes | ||
| Yes | 10 | None |
| Stool samples | ||
| Total | 627 | 1,417 |
| Before development of islet autoimmunity* | 339 | 692 |
| . | Case subjects . | Control subjects . |
|---|---|---|
| n | 27 | 53 |
| Age at onset of islet autoimmunity (months)* | 12.1 (5–37) | 12.3 (5–37) |
| Female sex | 17 (63) | 23 (43) |
| No. of other children in the family (siblings, half-siblings, step siblings) | ||
| None | 5 (18.5) | 16 (30.2) |
| ≥1 | 22 (81.5) | 37 (69.8) |
| First-degree relative with diabetes | ||
| None | 17 (63) | 50 (94.3) |
| Yes, of that | 10 (37) | 3 (5.7) |
| Sibling only | 3 | 0 |
| Father only | 3 | 2 |
| Mother only | 2 | 1 |
| Multiple family members | 2 | 0 |
| Progression from islet autoimmunity to type 1 diabetes | ||
| Yes | 10 | None |
| Stool samples | ||
| Total | 627 | 1,417 |
| Before development of islet autoimmunity* | 339 | 692 |
Data are median (range), n (%), and n.
*For matched control subjects: before the age at which the corresponding case subject seroconverted for islet autoantibodies.