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Table 1

Characteristics of three groups of patients (n = 1,005) with morbid obesity presenting with normal glucose tolerance, impaired glucose tolerance, or type 2 diabetes

NGTIGTType 2 diabetes
n 547 248 210 
Age (years) 37 ± 11 41 ± 11 47 ± 11 
BMI (kg/m244.2 ± 7.4 35.7 ± 13.0 45.8 ± 10.3 
Glucose (mg/dL)    
 Fasting 85 ± 8* 101 ± 12† 156 ± 55 
 1-h 139 ± 35* 185 ± 40† 246 ± 72 
 2-h 98 ± 22* 148 ± 32† 238 ± 61 
Insulin (µU/mL)    
 Fasting 23.1 ± 15.7* 30.5 ± 22.2 34.2 ± 27.8 
 1-h 141.5 ± 92.9 158.9 ± 97.2 134.7 ± 75.3 
 2-h 141.5 ± 92.9* 144.7 ± 126.4 161.2 ± 110.4 
HOMA-IR 4.8 ± 3.5* 7.6 ± 5.5† 11.8 ± 10.9 
HbA1c (%) 5.5 ± 0.5* 5.8 ± 0.5† 7.8 ± 1.7 
NGTIGTType 2 diabetes
n 547 248 210 
Age (years) 37 ± 11 41 ± 11 47 ± 11 
BMI (kg/m244.2 ± 7.4 35.7 ± 13.0 45.8 ± 10.3 
Glucose (mg/dL)    
 Fasting 85 ± 8* 101 ± 12† 156 ± 55 
 1-h 139 ± 35* 185 ± 40† 246 ± 72 
 2-h 98 ± 22* 148 ± 32† 238 ± 61 
Insulin (µU/mL)    
 Fasting 23.1 ± 15.7* 30.5 ± 22.2 34.2 ± 27.8 
 1-h 141.5 ± 92.9 158.9 ± 97.2 134.7 ± 75.3 
 2-h 141.5 ± 92.9* 144.7 ± 126.4 161.2 ± 110.4 
HOMA-IR 4.8 ± 3.5* 7.6 ± 5.5† 11.8 ± 10.9 
HbA1c (%) 5.5 ± 0.5* 5.8 ± 0.5† 7.8 ± 1.7 

Data are means ± SD. In between group differences were analyzed by Student unpaired t test. An α-level <0.05 was considered statistically significant. HOMA-IR, homeostasis model assessment of insulin resistance; IGT, impaired glucose tolerance; NGT, normal glucose tolerance.

*P < 0.001 normal glucose tolerance vs. type 2 diabetes.

P < 0.001 impaired glucose tolerance vs. type 2 diabetes.

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