American Diabetes Association

Table 4

cZ scores for autonomic small-fiber function, thermal somatic small- and large-fiber function

	Impaired awareness, mean ± SD	Normal awareness, mean ± SD	Mean difference (95% CI)	P value
Autonomic score*	0.42 ± 0.52	0.58 ± 0.61	−0.15 (−0.46, 0.16)	0.33
CAN† score	0.40 ± 0.73	0.53 ± 0.69	−0.13 (−0.45, 0.19)	0.42
Pupillometry score	0.43 ± 0.53	0.59 ± 0.73	−0.16 (−0.51, 0.20)	0.39
Thermal detection score	0.91 ± 1.04	0.75 ± 0.94	0.15 (−0.31, 0.61)	0.51
Nerve conduction score	1.71 ± 1.19	1.68 ± 1.10	0.03 (−0.43, 0.49)	0.89

	Impaired awareness, mean ± SD	Normal awareness, mean ± SD	Mean difference (95% CI)	P value
Autonomic score*	0.42 ± 0.52	0.58 ± 0.61	−0.15 (−0.46, 0.16)	0.33
CAN† score	0.40 ± 0.73	0.53 ± 0.69	−0.13 (−0.45, 0.19)	0.42
Pupillometry score	0.43 ± 0.53	0.59 ± 0.73	−0.16 (−0.51, 0.20)	0.39
Thermal detection score	0.91 ± 1.04	0.75 ± 0.94	0.15 (−0.31, 0.61)	0.51
Nerve conduction score	1.71 ± 1.19	1.68 ± 1.10	0.03 (−0.43, 0.49)	0.89

P values from paired Student t test.

*Combining CAN and pupillometry scores.

†Cardiovascular autonomic tests.