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Table 1

Clinical characteristics at baseline and end of study

Baseline90th weekP#
n (women/men) 86 (39/47) — — 
Age (years) 58 ± 9 — — 
Height (cm) 169 ± 11 — — 
Body weight (kg) 85.9 ± 18.2 82.7 ± 17.3 <0.0001 
BMI (kg/m2) 29.8 ± 4.5 28.7 ± 4.1 <0.0001 
HbA1c (%) [mmol/mol] 7.8 ± 0.8 [62 ± 9] 7.1 ± 0.7 [54 ± 8] <0.0001 
LDL-cholesterol (mg/dL) 111 ± 32 117 ± 43 NS 
HDL-cholesterol (mg/dL) 48 ± 11 55 ± 14 <0.001 
Triglycerides (mg/dL) 194 ± 175 181 ± 89 NS 
eGFR (mL · min−1 · 1.73 m−2) 89 ± 19 84 ± 18 0.0003 
FPG (mg/dL) 169 ± 41 143 ± 22 <0.0001 
Fat-free mass (kg) 55.3 ± 12.5 54.4 ± 12.4 <0.0001 
Fat mass (kg) 30.6 ± 10.2 28.4 ± 9.2 <0.0001 
TDEE (kcal/day) 2,139 [693] 2,192 [652] 0.0037 
Baseline90th weekP#
n (women/men) 86 (39/47) — — 
Age (years) 58 ± 9 — — 
Height (cm) 169 ± 11 — — 
Body weight (kg) 85.9 ± 18.2 82.7 ± 17.3 <0.0001 
BMI (kg/m2) 29.8 ± 4.5 28.7 ± 4.1 <0.0001 
HbA1c (%) [mmol/mol] 7.8 ± 0.8 [62 ± 9] 7.1 ± 0.7 [54 ± 8] <0.0001 
LDL-cholesterol (mg/dL) 111 ± 32 117 ± 43 NS 
HDL-cholesterol (mg/dL) 48 ± 11 55 ± 14 <0.001 
Triglycerides (mg/dL) 194 ± 175 181 ± 89 NS 
eGFR (mL · min−1 · 1.73 m−2) 89 ± 19 84 ± 18 0.0003 
FPG (mg/dL) 169 ± 41 143 ± 22 <0.0001 
Fat-free mass (kg) 55.3 ± 12.5 54.4 ± 12.4 <0.0001 
Fat mass (kg) 30.6 ± 10.2 28.4 ± 9.2 <0.0001 
TDEE (kcal/day) 2,139 [693] 2,192 [652] 0.0037 

Data are mean ± SD or median [IQR].

#Wilcoxon signed rank test.

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