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Table 2

Plasma glucose recovery

Dasiglucagon (n = 82)Placebo (n = 43)Glucagon (n = 43)
Time to recovery,* minutes (primary end point) 10 (10, 10) 40 (30, 40) 12 (10, 12) 
 P < 0.001   
True time to recovery* estimated using linear interpolation, minutes 9.0 (8.4, 9.7) 33.7 (26.1, 36.1) 10.0 (9.0, 10.6) 
 P < 0.001   
Proportion of patients achieving plasma glucose recovery* within, %    
 30 min 100 47 100 
 20 min 99 14 98 
 15 min 99 95 
 10 min 65 49 
 P < 0.001 for all tests 
Dasiglucagon (n = 82)Placebo (n = 43)Glucagon (n = 43)
Time to recovery,* minutes (primary end point) 10 (10, 10) 40 (30, 40) 12 (10, 12) 
 P < 0.001   
True time to recovery* estimated using linear interpolation, minutes 9.0 (8.4, 9.7) 33.7 (26.1, 36.1) 10.0 (9.0, 10.6) 
 P < 0.001   
Proportion of patients achieving plasma glucose recovery* within, %    
 30 min 100 47 100 
 20 min 99 14 98 
 15 min 99 95 
 10 min 65 49 
 P < 0.001 for all tests 

Data are median (95% CI) unless otherwise indicated.

*

Defined as first increase in plasma glucose of ≥20 mg/dL from baseline without administration of rescue intravenous glucose (censoring at 45 min).

Test relative to placebo.

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