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Table 2 —

Correlation coefficients determined by simple regression analyses between log-transformed plasma tHcy levels and clinical variables for all 75 diabetic subjects and those of 59 type 2 diabetic subjects with creatinine clearance >60 ml/min

All diabetic subjects
Diabetic subjects with creatinine clearance >60 ml/min
rPrP
Age 0.397 0.0004 0.223 0.089 
BMI 0.221 0.057 0.205 0.120 
Duration of diabetes 0.218 0.060 −0.100 0.450 
Smoking index 0.075 0.524 0.261 0.046* 
Systolic blood pressure 0.495 <0.0001 0.167 0.207 
Diastolic blood pressure 0.153 0.188 0.120 0.365 
HbA1c −0.377 0.0009 −0.229 0.081 
Fasting plasma insulin 0.182 0.118 0.125 0.344 
Uric acid 0.539 <0.0001 0.255 0.051 
Serum creatinine 0.636 <0.0001 0.388 0.002 
Total cholesterol −0.036 0.761 −0.005 0.970 
HDL cholesterol −0.294 0.010* −0.171 0.195 
Triglyceride 0.172 0.140 0.165 0.213 
Log vitamin B12 −0.142 0.248 −0.258 0.060 
Log folate −0.118 0.338 −0.267 0.051 
Creatinine clearance −0.634 <0.0001 −0.206 0.117 
Insulin sensitivity index −0.319 0.0054 0.237 0.070 
All diabetic subjects
Diabetic subjects with creatinine clearance >60 ml/min
rPrP
Age 0.397 0.0004 0.223 0.089 
BMI 0.221 0.057 0.205 0.120 
Duration of diabetes 0.218 0.060 −0.100 0.450 
Smoking index 0.075 0.524 0.261 0.046* 
Systolic blood pressure 0.495 <0.0001 0.167 0.207 
Diastolic blood pressure 0.153 0.188 0.120 0.365 
HbA1c −0.377 0.0009 −0.229 0.081 
Fasting plasma insulin 0.182 0.118 0.125 0.344 
Uric acid 0.539 <0.0001 0.255 0.051 
Serum creatinine 0.636 <0.0001 0.388 0.002 
Total cholesterol −0.036 0.761 −0.005 0.970 
HDL cholesterol −0.294 0.010* −0.171 0.195 
Triglyceride 0.172 0.140 0.165 0.213 
Log vitamin B12 −0.142 0.248 −0.258 0.060 
Log folate −0.118 0.338 −0.267 0.051 
Creatinine clearance −0.634 <0.0001 −0.206 0.117 
Insulin sensitivity index −0.319 0.0054 0.237 0.070 

The serum levels of vitamin B12 and folate were log-transformed (log vitamin B12 and log folate, respectively). Creatinine clearance was estimated by Cockcroft-Gault derived equation. Simple correlation coefficients are shown with level of significance.

*

P < 0.05;

P < 0.01;

P < 0.0001.

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