Pathogenesis of LADA
Factors involved in partial and/or slow progression of β-cell destruction |
Genetic predisposition to type 1 diabetes less marked |
Possible contribution of protective genes toward β-cell destruction |
Partial regeneration of β-cells |
Induction of immune tolerance once the immune process toward β-cells has initiated |
Quantitative/qualitative reduction in the exposure to environmental factors damaging the β-cells |
Factors involved in partial and/or slow progression of β-cell destruction |
Genetic predisposition to type 1 diabetes less marked |
Possible contribution of protective genes toward β-cell destruction |
Partial regeneration of β-cells |
Induction of immune tolerance once the immune process toward β-cells has initiated |
Quantitative/qualitative reduction in the exposure to environmental factors damaging the β-cells |