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Table 1 —

Demographic, genotypic, and biochemical characteristics of participants according to sex

MenWomenP
n 762 922 — 
Ala54 homozygotes (%) 396 (52.8) 484 (52.4) — 
Thr54 carriers (%) 366 (47.2) 438 (47.6) 0.8330 
Age (years) 56.3 ± 10.0 55.4 ± 9.8 0.0514 
BMI (kg/m228.3 ± 4.2 26.7 ± 5.5 0.0001 
Fasting glucose (mmol/l) 5.82 ± 1.88 5.42 ± 1.47 0.0001 
Fasting insulin (μU/ml) 32.7 ± 18.9 30.0 ± 28.4 0.0311 
2-h glucose (mmol/l) 6.19 ± 2.82 6.19 ± 2.25 0.9913 
2-h insulin (μU/ml) 98.1 ± 81.9 98.4 ± 67.4 0.9412 
HbA1c (%) 5.52 ± 1.20 5.43 ± 0.88 0.0834 
TGs (mmol/l) 1.71 ± 1.11 1.53 ± 1.24 0.0001 
Total cholesterol (mmol/l) 5.18 ± 0.85 5.36 ± 0.96 0.0001 
LDL cholesterol (mmol/l) 3.29 ± 0.76 3.20 ± 0.87 0.0376 
HDL cholesterol (mmol/l) 1.14 ± 0.31 1.47 ± 0.41 0.0001 
Alcohol (ounces/week) 3.6 ± 4.6 1.7 ± 2.4 0.0001 
Cigarettes/day 4.3 ± 10.7 3.7 ± 9.1 0.1882 
Postmenopausal (%) — 67.4 — 
On estrogen Rx (%)* — 19.7 — 
MenWomenP
n 762 922 — 
Ala54 homozygotes (%) 396 (52.8) 484 (52.4) — 
Thr54 carriers (%) 366 (47.2) 438 (47.6) 0.8330 
Age (years) 56.3 ± 10.0 55.4 ± 9.8 0.0514 
BMI (kg/m228.3 ± 4.2 26.7 ± 5.5 0.0001 
Fasting glucose (mmol/l) 5.82 ± 1.88 5.42 ± 1.47 0.0001 
Fasting insulin (μU/ml) 32.7 ± 18.9 30.0 ± 28.4 0.0311 
2-h glucose (mmol/l) 6.19 ± 2.82 6.19 ± 2.25 0.9913 
2-h insulin (μU/ml) 98.1 ± 81.9 98.4 ± 67.4 0.9412 
HbA1c (%) 5.52 ± 1.20 5.43 ± 0.88 0.0834 
TGs (mmol/l) 1.71 ± 1.11 1.53 ± 1.24 0.0001 
Total cholesterol (mmol/l) 5.18 ± 0.85 5.36 ± 0.96 0.0001 
LDL cholesterol (mmol/l) 3.29 ± 0.76 3.20 ± 0.87 0.0376 
HDL cholesterol (mmol/l) 1.14 ± 0.31 1.47 ± 0.41 0.0001 
Alcohol (ounces/week) 3.6 ± 4.6 1.7 ± 2.4 0.0001 
Cigarettes/day 4.3 ± 10.7 3.7 ± 9.1 0.1882 
Postmenopausal (%) — 67.4 — 
On estrogen Rx (%)* — 19.7 — 

Data are n (%) or means ± SD, unless otherwise stated.

*

Includes hormonal replacement therapy and the use of oral contraceptives.

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