Demographic, genotypic, and biochemical characteristics of participants according to sex
| . | Men . | Women . | P . |
|---|---|---|---|
| n | 762 | 922 | — |
| Ala54 homozygotes (%) | 396 (52.8) | 484 (52.4) | — |
| Thr54 carriers (%) | 366 (47.2) | 438 (47.6) | 0.8330 |
| Age (years) | 56.3 ± 10.0 | 55.4 ± 9.8 | 0.0514 |
| BMI (kg/m2) | 28.3 ± 4.2 | 26.7 ± 5.5 | 0.0001 |
| Fasting glucose (mmol/l) | 5.82 ± 1.88 | 5.42 ± 1.47 | 0.0001 |
| Fasting insulin (μU/ml) | 32.7 ± 18.9 | 30.0 ± 28.4 | 0.0311 |
| 2-h glucose (mmol/l) | 6.19 ± 2.82 | 6.19 ± 2.25 | 0.9913 |
| 2-h insulin (μU/ml) | 98.1 ± 81.9 | 98.4 ± 67.4 | 0.9412 |
| HbA1c (%) | 5.52 ± 1.20 | 5.43 ± 0.88 | 0.0834 |
| TGs (mmol/l) | 1.71 ± 1.11 | 1.53 ± 1.24 | 0.0001 |
| Total cholesterol (mmol/l) | 5.18 ± 0.85 | 5.36 ± 0.96 | 0.0001 |
| LDL cholesterol (mmol/l) | 3.29 ± 0.76 | 3.20 ± 0.87 | 0.0376 |
| HDL cholesterol (mmol/l) | 1.14 ± 0.31 | 1.47 ± 0.41 | 0.0001 |
| Alcohol (ounces/week) | 3.6 ± 4.6 | 1.7 ± 2.4 | 0.0001 |
| Cigarettes/day | 4.3 ± 10.7 | 3.7 ± 9.1 | 0.1882 |
| Postmenopausal (%) | — | 67.4 | — |
| On estrogen Rx (%)* | — | 19.7 | — |
| . | Men . | Women . | P . |
|---|---|---|---|
| n | 762 | 922 | — |
| Ala54 homozygotes (%) | 396 (52.8) | 484 (52.4) | — |
| Thr54 carriers (%) | 366 (47.2) | 438 (47.6) | 0.8330 |
| Age (years) | 56.3 ± 10.0 | 55.4 ± 9.8 | 0.0514 |
| BMI (kg/m2) | 28.3 ± 4.2 | 26.7 ± 5.5 | 0.0001 |
| Fasting glucose (mmol/l) | 5.82 ± 1.88 | 5.42 ± 1.47 | 0.0001 |
| Fasting insulin (μU/ml) | 32.7 ± 18.9 | 30.0 ± 28.4 | 0.0311 |
| 2-h glucose (mmol/l) | 6.19 ± 2.82 | 6.19 ± 2.25 | 0.9913 |
| 2-h insulin (μU/ml) | 98.1 ± 81.9 | 98.4 ± 67.4 | 0.9412 |
| HbA1c (%) | 5.52 ± 1.20 | 5.43 ± 0.88 | 0.0834 |
| TGs (mmol/l) | 1.71 ± 1.11 | 1.53 ± 1.24 | 0.0001 |
| Total cholesterol (mmol/l) | 5.18 ± 0.85 | 5.36 ± 0.96 | 0.0001 |
| LDL cholesterol (mmol/l) | 3.29 ± 0.76 | 3.20 ± 0.87 | 0.0376 |
| HDL cholesterol (mmol/l) | 1.14 ± 0.31 | 1.47 ± 0.41 | 0.0001 |
| Alcohol (ounces/week) | 3.6 ± 4.6 | 1.7 ± 2.4 | 0.0001 |
| Cigarettes/day | 4.3 ± 10.7 | 3.7 ± 9.1 | 0.1882 |
| Postmenopausal (%) | — | 67.4 | — |
| On estrogen Rx (%)* | — | 19.7 | — |
Data are n (%) or means ± SD, unless otherwise stated.
Includes hormonal replacement therapy and the use of oral contraceptives.