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Table 2 —

Characteristics of FOS subjects according to FABP2 allele

ala54 Homozygotesthr54 CarriersP*
Men    
n 396 366 — 
 Age (years) 56.1 ± 10.1 56.5 ± 10.0 0.6076 
 BMI (kg/m228.6 ± 4.3 28.0 ± 4.1 0.1850 
 TGs (mmol/l) 1.77 ± 1.26 1.66 ± 0.93 0.3658 
 Total cholesterol (mmol/l) 5.17 ± 0.86 5.20 ± 0.84 0.4481 
 LDL cholesterol (mmol/l) 3.26 ± 0.77 3.32 ± 0.76 0.2407 
 HDL cholesterol (mmol/l) 1.13 ± 0.32 1.14 ± 0.28 0.4790 
 Fasting glucose (mmol/l) 5.77 ± 1.67 5.87 ± 2.07 0.1198 
 Fasting insulin (μU/ml) 33.3 ± 16.5 32.0 ± 21.3 0.8110 
 2-h glucose (mmol/l) 6.21 ± 2.47 6.16 ± 3.14 0.7449 
 2-h insulin (μU/ml) 104.4 ± 86.6 91.3 ± 76.1 0.1141 
 HbA1c (%) 5.53 ± 1.17 5.52 ± 1.25 0.8843 
Women    
n 484 438 — 
 Age (years) 54.9 ± 9.9 55.9 ± 9.8 0.1200 
 BMI (kg/m226.9 ± 5.6 26.4 ± 5.3 0.2392 
 Triglycerides (mmol/l) 1.54 ± 1.49 1.52 ± 0.89 0.8211 
 Total cholesterol (mmol/l) 5.30 ± 0.98 5.42 ± 0.93 0.0418 
 LDL cholesterol (mmol/l) 3.15 ± 0.89 3.26 ± 0.85 0.0308 
 HDL cholesterol (mmol/l) 1.45 ± 0.40 1.48 ± 0.42 0.3763 
 Fasting glucose (mmol/l) 5.43 ± 1.57 5.40 ± 1.36 0.7331 
 Fasting insulin (μU/ml) 28.8 ± 16.4 31.4 ± 37.4 0.0708 
 2-h glucose (mmol/l) 6.06 ± 2.02 6.33 ± 2.48 0.2578 
 2-h insulin (μU/ml) 93.4 ± 61.5 104.0 ± 73.0 0.0139 
 HbA1c (%) 5.45 ± 0.91 5.41 ± 0.85 0.5167 
ala54 Homozygotesthr54 CarriersP*
Men    
n 396 366 — 
 Age (years) 56.1 ± 10.1 56.5 ± 10.0 0.6076 
 BMI (kg/m228.6 ± 4.3 28.0 ± 4.1 0.1850 
 TGs (mmol/l) 1.77 ± 1.26 1.66 ± 0.93 0.3658 
 Total cholesterol (mmol/l) 5.17 ± 0.86 5.20 ± 0.84 0.4481 
 LDL cholesterol (mmol/l) 3.26 ± 0.77 3.32 ± 0.76 0.2407 
 HDL cholesterol (mmol/l) 1.13 ± 0.32 1.14 ± 0.28 0.4790 
 Fasting glucose (mmol/l) 5.77 ± 1.67 5.87 ± 2.07 0.1198 
 Fasting insulin (μU/ml) 33.3 ± 16.5 32.0 ± 21.3 0.8110 
 2-h glucose (mmol/l) 6.21 ± 2.47 6.16 ± 3.14 0.7449 
 2-h insulin (μU/ml) 104.4 ± 86.6 91.3 ± 76.1 0.1141 
 HbA1c (%) 5.53 ± 1.17 5.52 ± 1.25 0.8843 
Women    
n 484 438 — 
 Age (years) 54.9 ± 9.9 55.9 ± 9.8 0.1200 
 BMI (kg/m226.9 ± 5.6 26.4 ± 5.3 0.2392 
 Triglycerides (mmol/l) 1.54 ± 1.49 1.52 ± 0.89 0.8211 
 Total cholesterol (mmol/l) 5.30 ± 0.98 5.42 ± 0.93 0.0418 
 LDL cholesterol (mmol/l) 3.15 ± 0.89 3.26 ± 0.85 0.0308 
 HDL cholesterol (mmol/l) 1.45 ± 0.40 1.48 ± 0.42 0.3763 
 Fasting glucose (mmol/l) 5.43 ± 1.57 5.40 ± 1.36 0.7331 
 Fasting insulin (μU/ml) 28.8 ± 16.4 31.4 ± 37.4 0.0708 
 2-h glucose (mmol/l) 6.06 ± 2.02 6.33 ± 2.48 0.2578 
 2-h insulin (μU/ml) 93.4 ± 61.5 104.0 ± 73.0 0.0139 
 HbA1c (%) 5.45 ± 0.91 5.41 ± 0.85 0.5167 

Data are n or means ± SD, unless otherwise stated.

*

After adjustment for familial relationship, age, BMI, TGs, APOE genotype, smoking, alcohol intake, and use of β-blockers (and menopausal status and estrogen therapy in women);

P < 0.05.

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