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Table 2—

Distribution of fat measures and adipocytokines for women and men in the Health ABC study

Women
Men
Diabetes (case subjects)No diabetes (control subjects)P valueDiabetes (case subjects)No diabetes (control subjects)P value
n 221 221  298 298  
BMI (kg/m230.8 ± 5.7 27.5 ± 5.8 <0.001 28.5 ± 4.1 26.7 ± 3.9 <0.001 
Waist circumference (cm) 105.5 ± 13.2 97.3 ± 14.1 <0.001 104.3 ± 12.5 98.9 ± 11.9 <0.001 
Total fat mass (kg) 32.2 ± 9.6 28.3 ± 9.8 <0.001 25.1 ± 7.5 22.4 ± 7.1 <0.001 
Total percent fat mass (%) 40.2 ± 5.6 39.1 ± 6.4 0.08 28.8 ± 5.1 27.5 ± 5.3 0.003 
Abdominal subcutaneous fat area (cm2387.1 ± 128.4 345.2 ± 137.7 0.001 248.9 ± 93.1 224.5 ± 92.4 0.001 
Abdominal visceral fat area (cm2165.9 ± 66.5 109.8 ± 47.8 <0.001 177.7 ± 80.7 141.7 ± 69.1 <0.001 
Thigh intermuscular fat area (cm213.3 ± 6.8 10.7 ± 6.7 <0.001 12.1 ± 8.9 9.5 ± 6.1 <0.001 
Thigh subcutaneous fat area (cm2112.4 ± 53.0 111.1 ± 50.0 0.79 47.1 ± 20.5 48.9 ± 21.3 0.30 
Adipocytokines*       
Adiponectin (μg/ml) 7 (5–11) 11 (7–15) <0.001 6 (4–8) 8 (5–12) <0.001 
Leptin (ng/ml) 20.4 (11.8–29.6) 17.0 (10.4–27.2) 0.03 7.5 (4.6–12.3) 5.5 (3.3–9.4) <0.001 
IL-6 (pg/ml) 2.3 (1.6–3.6) 1.6 (1.1–2.4) <0.001 2.2 (1.6–3.2) 1.7 (1.3–2.5) <0.001 
PAI-1 (ng/ml) 33 (18–53) 20 (12–35) <0.001 26 (16–45.7) 17 (10–28) <0.001 
TNF-α (pg/ml) 3.4 (2.6–4.5) 2.7 (2.1–3.9) <0.001 3.6 (2.7–4.7) 3.1 (2.4–3.8) <0.001 
Women
Men
Diabetes (case subjects)No diabetes (control subjects)P valueDiabetes (case subjects)No diabetes (control subjects)P value
n 221 221  298 298  
BMI (kg/m230.8 ± 5.7 27.5 ± 5.8 <0.001 28.5 ± 4.1 26.7 ± 3.9 <0.001 
Waist circumference (cm) 105.5 ± 13.2 97.3 ± 14.1 <0.001 104.3 ± 12.5 98.9 ± 11.9 <0.001 
Total fat mass (kg) 32.2 ± 9.6 28.3 ± 9.8 <0.001 25.1 ± 7.5 22.4 ± 7.1 <0.001 
Total percent fat mass (%) 40.2 ± 5.6 39.1 ± 6.4 0.08 28.8 ± 5.1 27.5 ± 5.3 0.003 
Abdominal subcutaneous fat area (cm2387.1 ± 128.4 345.2 ± 137.7 0.001 248.9 ± 93.1 224.5 ± 92.4 0.001 
Abdominal visceral fat area (cm2165.9 ± 66.5 109.8 ± 47.8 <0.001 177.7 ± 80.7 141.7 ± 69.1 <0.001 
Thigh intermuscular fat area (cm213.3 ± 6.8 10.7 ± 6.7 <0.001 12.1 ± 8.9 9.5 ± 6.1 <0.001 
Thigh subcutaneous fat area (cm2112.4 ± 53.0 111.1 ± 50.0 0.79 47.1 ± 20.5 48.9 ± 21.3 0.30 
Adipocytokines*       
Adiponectin (μg/ml) 7 (5–11) 11 (7–15) <0.001 6 (4–8) 8 (5–12) <0.001 
Leptin (ng/ml) 20.4 (11.8–29.6) 17.0 (10.4–27.2) 0.03 7.5 (4.6–12.3) 5.5 (3.3–9.4) <0.001 
IL-6 (pg/ml) 2.3 (1.6–3.6) 1.6 (1.1–2.4) <0.001 2.2 (1.6–3.2) 1.7 (1.3–2.5) <0.001 
PAI-1 (ng/ml) 33 (18–53) 20 (12–35) <0.001 26 (16–45.7) 17 (10–28) <0.001 
TNF-α (pg/ml) 3.4 (2.6–4.5) 2.7 (2.1–3.9) <0.001 3.6 (2.7–4.7) 3.1 (2.4–3.8) <0.001 

Data are n (%) or means ± SD.

*

Median (25–75%).

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