Skip to Main Content
Table 3—

Mean age-adjusted values of circulating and urinary TGF-β1 and Amadori albumin by albuminuria and retinopathy

nUrinary TGF-β1/creatinine (pg/mmol)Circulating TGF-β1 (ng/ml)Amadori albumin (units/ml)
Normoalbuminuria 326 2.6 (2.4–2.8) 5.6 (5.2–6.1) 43.2 (41.8–44.6) 
Microalbuminuria 81 3.7 (3.2–4.3) 6.4 (5.5–7.5) 47.8 (44.9–50.6) 
Macroalbuminuria 126 4.6 (4.1–5.2) 6.2 (5.5–7.0) 50.3 (48.1–52.6) 
P for macro- vs. normoalbuminuria — 0.0001 0.007 0.0001 
P for micro- vs. normoalbuminuria — 0.0001 0.5 0.004 
No retinopathy 235 2.5 (2.3–2.7) 5.7 (5.2–6.2) 43.5 (41.8–45.2) 
Background retinopathy 146 3.6 (3.2–4.1) 5.4 (4.8–6.1) 45.2 (43.0–47.3) 
Proliferative retinopathy 154 3.8 (3.4–4.3) 6.7 (6.0–7.4) 49.3 (47.2–51.4) 
P for trend — 0.0001 0.02 0.0001 
P for proliferative vs. none — 0.06 0.02 0.0001 
P for proliferative vs. none, adjusted for AER — 0.9 0.04 0.04 
nUrinary TGF-β1/creatinine (pg/mmol)Circulating TGF-β1 (ng/ml)Amadori albumin (units/ml)
Normoalbuminuria 326 2.6 (2.4–2.8) 5.6 (5.2–6.1) 43.2 (41.8–44.6) 
Microalbuminuria 81 3.7 (3.2–4.3) 6.4 (5.5–7.5) 47.8 (44.9–50.6) 
Macroalbuminuria 126 4.6 (4.1–5.2) 6.2 (5.5–7.0) 50.3 (48.1–52.6) 
P for macro- vs. normoalbuminuria — 0.0001 0.007 0.0001 
P for micro- vs. normoalbuminuria — 0.0001 0.5 0.004 
No retinopathy 235 2.5 (2.3–2.7) 5.7 (5.2–6.2) 43.5 (41.8–45.2) 
Background retinopathy 146 3.6 (3.2–4.1) 5.4 (4.8–6.1) 45.2 (43.0–47.3) 
Proliferative retinopathy 154 3.8 (3.4–4.3) 6.7 (6.0–7.4) 49.3 (47.2–51.4) 
P for trend — 0.0001 0.02 0.0001 
P for proliferative vs. none — 0.06 0.02 0.0001 
P for proliferative vs. none, adjusted for AER — 0.9 0.04 0.04 

Data are means (95% CI) unless otherwise indicated.

Close Modal

or Create an Account

Close Modal
Close Modal