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TABLE 3

Mean levels of risk variables in childhood by number of criterion risk variables present in adulthood*

Childhood risk variableNumber of criterion risk in adulthood
P (trend)
01234
n 310 208 112 67 48  
BMI (kg/m218.3 19.0 21.0 23.0 23.6 0.0001 
Insulin (μU/ml) 8.4 8.2 10.9 14.1 13.6 0.0001 
Glucose (mg/dl) 82.0 82.2 82.8 83.1 83.0 NS 
Systolic blood pressure (mmHg) 104.6 106.6 107.2 109.4 110.2 0.0001 
Diastolic blood pressure (mmHg) 64.7 65.0 65.4 66.7 68.3 0.01 
Mean arterial pressure (mmHg) 78.0 78.9 79.3 80.9 82.2 0.0001 
Cholesterol (mg/dl)       
 Total 156.2 159.8 161.3 163.8 162.6 0.01 
 LDL 86.1 93.1 98.3 99.7 102.3 0.0001 
 HDL 62.7 58.5 58.8 52.0 50.4 0.0001 
Triglycerides (mg/dl) 61.0 64.9 69.9 78.7 73.9 0.0001 
Total cholesterol/HDL cholesterol 2.7 3.2 3.7 4.6 3.9 0.0001 
Triglycerides/HDL cholesterol 1.2 1.6 1.9 2.7 2.0 0.0001 
Childhood risk variableNumber of criterion risk in adulthood
P (trend)
01234
n 310 208 112 67 48  
BMI (kg/m218.3 19.0 21.0 23.0 23.6 0.0001 
Insulin (μU/ml) 8.4 8.2 10.9 14.1 13.6 0.0001 
Glucose (mg/dl) 82.0 82.2 82.8 83.1 83.0 NS 
Systolic blood pressure (mmHg) 104.6 106.6 107.2 109.4 110.2 0.0001 
Diastolic blood pressure (mmHg) 64.7 65.0 65.4 66.7 68.3 0.01 
Mean arterial pressure (mmHg) 78.0 78.9 79.3 80.9 82.2 0.0001 
Cholesterol (mg/dl)       
 Total 156.2 159.8 161.3 163.8 162.6 0.01 
 LDL 86.1 93.1 98.3 99.7 102.3 0.0001 
 HDL 62.7 58.5 58.8 52.0 50.4 0.0001 
Triglycerides (mg/dl) 61.0 64.9 69.9 78.7 73.9 0.0001 
Total cholesterol/HDL cholesterol 2.7 3.2 3.7 4.6 3.9 0.0001 
Triglycerides/HDL cholesterol 1.2 1.6 1.9 2.7 2.0 0.0001 
*

The earliest childhood and latest adulthood measurements with a mean ± SD follow-up period of 11.6 ± 3.4 years were used;

adjusted for age at baseline, race, and sex;

number of any criterion risk variables (BMI, insulin, systolic blood pressure or mean arterial pressure, and total cholesterol/HDL cholesterol or triglycerides/HDL cholesterol) ≥75th percentile specific for age, race, sex, and survey year. NS, not significant.

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