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Table 1—

Parent and extension insulin lispro studies

Parent studies (A–H) and insulin treatment historyStudy design
Prior insulin treatment 1-year, parallel 
 Study A  Type 1 
 Study B  Type 2 
 Study C  Type 1 
 Study D  Type 2 
Insulin-naïve 1-year, parallel 
 Study E  Type 1 
 Study F  Type 2 
Prior insulin treatment 6-month, cross-over 
 Study G  Type 1 
 Study H  Type 2 
Parent studies (A–H) and insulin treatment historyStudy design
Prior insulin treatment 1-year, parallel 
 Study A  Type 1 
 Study B  Type 2 
 Study C  Type 1 
 Study D  Type 2 
Insulin-naïve 1-year, parallel 
 Study E  Type 1 
 Study F  Type 2 
Prior insulin treatment 6-month, cross-over 
 Study G  Type 1 
 Study H  Type 2 
Extension studies (K, O, M, N) (enrolled patients) age; gender; originDesign (completed patients)
Study K Single arm, up to 4 years 
 (271)  (214) 
 13.4–71.5 years; 53/47% M/F; 86.4% Caucasian  
Study O Single arm, up to 4 years 
 (167)  (121) 
 13.7–69.4 years; 60/40% M/F; 96.1% Caucasian  
Studies M and N Single arm, up to 4 years 
 (771)  (653) 
 13.7–80.7 years; 56/44% M/F; 95.4% Caucasian  
Extension studies (K, O, M, N) (enrolled patients) age; gender; originDesign (completed patients)
Study K Single arm, up to 4 years 
 (271)  (214) 
 13.4–71.5 years; 53/47% M/F; 86.4% Caucasian  
Study O Single arm, up to 4 years 
 (167)  (121) 
 13.7–69.4 years; 60/40% M/F; 96.1% Caucasian  
Studies M and N Single arm, up to 4 years 
 (771)  (653) 
 13.7–80.7 years; 56/44% M/F; 95.4% Caucasian  
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