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Table 1—

Characteristics of 18 patients and 20 wounds undergoing treatment with standard care or maggot therapy

Conventional therapyMDT
n wounds monitored 14 14 
 Duration (weeks) 40 (13.5; 4–312) 44 (21; 4–318) 
 Size (cm26.3 (6.6; 0.5–15.5) 13.3 (7.8; 0.9–42) 
 Circumference (cm) 9.4 (10.3; 2.5–16.6) 13.5 (10.7; 3.3–27.7) 
 Depth to periosteum or into bone (%) 14 21 
 Necrotic tissue (% total surface) 44 (35; 0–100) 38 (38; 0–90) 
 Granulation tissue (% total surface) 18 (0; 0–90) 19 (1; 0–100) 
Pathologic precursors (26)   
 Ischemic (%) 
 Neuropathic (%) 86 64 
 Mixed or undefined (%) 29 
Prior treatment (n [%])   
 Dry gauze, saline, petrolatum, aloe, other gel 3 (21.4) 3 (21.4) 
 Topical antimicrobial 1 (7.1) 1 (7.1) 
 Chemical debriding agent 1 (7.1) 
 Sharp debridement, incision and drainage, other surgical procedure 5 (35.7) 8 (57.1) 
 Three or more different nonsurgical methods 4 (28.6) 2 (14.3) 
Patient age (years) 68 (72; 53–82) 63 (62; 53–74) 
Underlying illnesses   
 Peripheral venous or arterial disease (%) 64 93 
 Cigarette smoker (%) 23 14 
 Mean ideal body weight (%) 114 129 
 Mean albumin (g/dl) 3.7 3.7 
 Mean hemoglobin (g/dl) 12.4 13.2 
 Receiving systemic antibiotics (n [%]) 2 (14) 3 (21) 
Conventional therapyMDT
n wounds monitored 14 14 
 Duration (weeks) 40 (13.5; 4–312) 44 (21; 4–318) 
 Size (cm26.3 (6.6; 0.5–15.5) 13.3 (7.8; 0.9–42) 
 Circumference (cm) 9.4 (10.3; 2.5–16.6) 13.5 (10.7; 3.3–27.7) 
 Depth to periosteum or into bone (%) 14 21 
 Necrotic tissue (% total surface) 44 (35; 0–100) 38 (38; 0–90) 
 Granulation tissue (% total surface) 18 (0; 0–90) 19 (1; 0–100) 
Pathologic precursors (26)   
 Ischemic (%) 
 Neuropathic (%) 86 64 
 Mixed or undefined (%) 29 
Prior treatment (n [%])   
 Dry gauze, saline, petrolatum, aloe, other gel 3 (21.4) 3 (21.4) 
 Topical antimicrobial 1 (7.1) 1 (7.1) 
 Chemical debriding agent 1 (7.1) 
 Sharp debridement, incision and drainage, other surgical procedure 5 (35.7) 8 (57.1) 
 Three or more different nonsurgical methods 4 (28.6) 2 (14.3) 
Patient age (years) 68 (72; 53–82) 63 (62; 53–74) 
Underlying illnesses   
 Peripheral venous or arterial disease (%) 64 93 
 Cigarette smoker (%) 23 14 
 Mean ideal body weight (%) 114 129 
 Mean albumin (g/dl) 3.7 3.7 
 Mean hemoglobin (g/dl) 12.4 13.2 
 Receiving systemic antibiotics (n [%]) 2 (14) 3 (21) 

Data are means (median and range), unless otherwise specified. Six wounds received conventional therapy only, six received maggot therapy only, and eight received conventional therapy followed by maggot therapy.

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