Renal response to hyperglycemia in groups segregated by N/D ratio
| Parameter . | Normal N/D ratio . | . | High N/D ratio . | . | ||
|---|---|---|---|---|---|---|
| . | Euglycemia . | Hyperglycemia . | Euglycemia . | Hyperglycemia . | ||
| GFR (ml · min−1 · 1.73 m−2) | 128 ± 46 | 127 ± 17 | 142 ± 31 | 157 ± 28*† | ||
| ERPF (ml · min−1 · 1.73 m−2) | 698 ± 124 | 502 ± 107 | 756 ± 242 | 704 ± 158 | ||
| RBF (ml · min−1 · 1.73 m−2) | 1,113 ± 183 | 1,006 ± 121 | 1,250 ± 454 | 1,166 ± 289 | ||
| FF | 0.18 ± 0.05 | 0.21 ± 0.03 | 0.20 ± 0.05 | 0.23 ± 0.05 | ||
| RVR (mmHg · l−1 · min−1) | 77 ± 13 | 84 ± 18 | 64 ± 16‡ | 67 ± 9† | ||
| MAP (mmHg) | 83 ± 5 | 83 ± 9 | 74 ± 9‡ | 75 ± 9 | ||
| Parameter . | Normal N/D ratio . | . | High N/D ratio . | . | ||
|---|---|---|---|---|---|---|
| . | Euglycemia . | Hyperglycemia . | Euglycemia . | Hyperglycemia . | ||
| GFR (ml · min−1 · 1.73 m−2) | 128 ± 46 | 127 ± 17 | 142 ± 31 | 157 ± 28*† | ||
| ERPF (ml · min−1 · 1.73 m−2) | 698 ± 124 | 502 ± 107 | 756 ± 242 | 704 ± 158 | ||
| RBF (ml · min−1 · 1.73 m−2) | 1,113 ± 183 | 1,006 ± 121 | 1,250 ± 454 | 1,166 ± 289 | ||
| FF | 0.18 ± 0.05 | 0.21 ± 0.03 | 0.20 ± 0.05 | 0.23 ± 0.05 | ||
| RVR (mmHg · l−1 · min−1) | 77 ± 13 | 84 ± 18 | 64 ± 16‡ | 67 ± 9† | ||
| MAP (mmHg) | 83 ± 5 | 83 ± 9 | 74 ± 9‡ | 75 ± 9 | ||
Data are means ± SE.
P < 0.05 vs. baseline;
P < 0.05 vs. response of normal N/D ratio group;
P < 0.05 vs. baseline value of normal N/D ratio group.