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TABLE 2

Renal response to hyperglycemia in groups segregated by N/D ratio

ParameterNormal N/D ratio
High N/D ratio
EuglycemiaHyperglycemiaEuglycemiaHyperglycemia
GFR (ml · min−1 · 1.73 m−2128 ± 46 127 ± 17 142 ± 31 157 ± 28* 
ERPF (ml · min−1 · 1.73 m−2698 ± 124 502 ± 107 756 ± 242 704 ± 158 
RBF (ml · min−1 · 1.73 m−21,113 ± 183 1,006 ± 121 1,250 ± 454 1,166 ± 289 
FF 0.18 ± 0.05 0.21 ± 0.03 0.20 ± 0.05 0.23 ± 0.05 
RVR (mmHg · l−1 · min−177 ± 13 84 ± 18 64 ± 16 67 ± 9 
MAP (mmHg) 83 ± 5 83 ± 9 74 ± 9 75 ± 9 
ParameterNormal N/D ratio
High N/D ratio
EuglycemiaHyperglycemiaEuglycemiaHyperglycemia
GFR (ml · min−1 · 1.73 m−2128 ± 46 127 ± 17 142 ± 31 157 ± 28* 
ERPF (ml · min−1 · 1.73 m−2698 ± 124 502 ± 107 756 ± 242 704 ± 158 
RBF (ml · min−1 · 1.73 m−21,113 ± 183 1,006 ± 121 1,250 ± 454 1,166 ± 289 
FF 0.18 ± 0.05 0.21 ± 0.03 0.20 ± 0.05 0.23 ± 0.05 
RVR (mmHg · l−1 · min−177 ± 13 84 ± 18 64 ± 16 67 ± 9 
MAP (mmHg) 83 ± 5 83 ± 9 74 ± 9 75 ± 9 

Data are means ± SE.

*

P < 0.05 vs. baseline;

P < 0.05 vs. response of normal N/D ratio group;

P < 0.05 vs. baseline value of normal N/D ratio group.

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