Genotype and allele frequencies of the examined variants in SLC2A10 among type 2 diabetic patients and glucose-tolerant subjects
| . | Type 2 diabetic patients . | Glucose-tolerant subjects . | PAF . | PGD . |
|---|---|---|---|---|
| −27C→T | ||||
| C/C | 466 (97) | 488 (98) | ||
| C/T | 13 (3) | 12 (2) | ||
| T/T | 0 (0) | 0 (0) | ||
| Allele frequency | 1.4 (0.6–2.1) | 1.2 (0.5–1.9) | 0.8 | 0.8 |
| Ala206Thr | ||||
| Ala/Ala | 455 (91) | 469 (92) | ||
| Ala/Thr | 42 (8) | 36 (7) | ||
| Thr/Thr | 2 (0) | 2 (0) | ||
| Allele frequency | 4.6 (3.3–5.9) | 3.9 (2.7–5.1) | 0.5 | 0.8 |
| IVS2 + 10G→A | ||||
| G/G | 450 (96) | 474 (97) | ||
| G/A | 20 (4) | 15 (3) | ||
| A/A | 1 (0) | 1 (0) | ||
| Allele frequency | 2.3 (1.4–3.3) | 1.7 (0.9–2.6) | 0.4 | 0.7 |
| IVS4 + 18T→G | ||||
| T/T | 162 (33) | 174 (40) | ||
| T/G | 248 (50) | 190 (43) | ||
| G/G | 85 (17) | 73 (17) | ||
| Allele frequency | 42.2 (39.1–45.3) | 38.4 (35.2–41.7) | 0.1 | 0.07 |
| . | Type 2 diabetic patients . | Glucose-tolerant subjects . | PAF . | PGD . |
|---|---|---|---|---|
| −27C→T | ||||
| C/C | 466 (97) | 488 (98) | ||
| C/T | 13 (3) | 12 (2) | ||
| T/T | 0 (0) | 0 (0) | ||
| Allele frequency | 1.4 (0.6–2.1) | 1.2 (0.5–1.9) | 0.8 | 0.8 |
| Ala206Thr | ||||
| Ala/Ala | 455 (91) | 469 (92) | ||
| Ala/Thr | 42 (8) | 36 (7) | ||
| Thr/Thr | 2 (0) | 2 (0) | ||
| Allele frequency | 4.6 (3.3–5.9) | 3.9 (2.7–5.1) | 0.5 | 0.8 |
| IVS2 + 10G→A | ||||
| G/G | 450 (96) | 474 (97) | ||
| G/A | 20 (4) | 15 (3) | ||
| A/A | 1 (0) | 1 (0) | ||
| Allele frequency | 2.3 (1.4–3.3) | 1.7 (0.9–2.6) | 0.4 | 0.7 |
| IVS4 + 18T→G | ||||
| T/T | 162 (33) | 174 (40) | ||
| T/G | 248 (50) | 190 (43) | ||
| G/G | 85 (17) | 73 (17) | ||
| Allele frequency | 42.2 (39.1–45.3) | 38.4 (35.2–41.7) | 0.1 | 0.07 |
Data are number of subjects with each genotype (% of each group) and allele frequencies of minor allele in % (95% CI). The P values compare allele frequencies (PAF) and genotype distributions (PGD) between type 2 diabetic patients and glucose-tolerant subjects. All genotype groups obeyed Hardy-Weinberg equilibrium.