Linkage of adiponectin
| Chromosome . | Peak of LOD score (cM) . | Flanking markers (position) . | Siblings without diabetes . | . | Siblings without diabetes or with diabetes not treated pharmacologically . | . | ||
|---|---|---|---|---|---|---|---|---|
| . | . | . | Model 1 . | Model 2 . | Model 1 . | Model 2 . | ||
| 2 | 89 | D2S1777 (88 cM), D2S428 (93 cM) | 1.7 | 1.6 | 0.9 | 1.6 | ||
| 3 | 124 | D3S4018 (121 cM), D3S1769 (129 cM) | 1.0 | 0.8 | 1.9 | 1.8 | ||
| 9 | 18 | D9S168 (10 cM), D9S925 (24 cM) | 3.0 | 1.7 | 3.5 | 1.7 | ||
| 10 | 70 | D10S1426 (64 cM), D10S1220 (75 cM) | 0.9 | 1.0 | 1.7 | 1.0 | ||
| Chromosome . | Peak of LOD score (cM) . | Flanking markers (position) . | Siblings without diabetes . | . | Siblings without diabetes or with diabetes not treated pharmacologically . | . | ||
|---|---|---|---|---|---|---|---|---|
| . | . | . | Model 1 . | Model 2 . | Model 1 . | Model 2 . | ||
| 2 | 89 | D2S1777 (88 cM), D2S428 (93 cM) | 1.7 | 1.6 | 0.9 | 1.6 | ||
| 3 | 124 | D3S4018 (121 cM), D3S1769 (129 cM) | 1.0 | 0.8 | 1.9 | 1.8 | ||
| 9 | 18 | D9S168 (10 cM), D9S925 (24 cM) | 3.0 | 1.7 | 3.5 | 1.7 | ||
| 10 | 70 | D10S1426 (64 cM), D10S1220 (75 cM) | 0.9 | 1.0 | 1.7 | 1.0 | ||
Linkage results of adiponectin adjusted by linear regression for age and sex (model 1) or age, sex, and BMI (model 2) in subjects without diabetes (517 individuals from 162 families, 750 sib-pairs) or with inclusion of 45 siblings with diet-treated type 2 diabetes (total siblings 582, 182 families, 860 sib-pairs).