American Diabetes Association

TABLE 1

Allelic frequencies for SNPs in an obesity case-control material

SNP	Major/minor allele	Lean			Obese			McNeamar P value	χ²	Permutation P value
SNP	Major/minor allele			1	2	1	2	McNeamar P value	χ²	Permutation P value
rs9626055	C/T	0.979	0.021	0.979	0.021	1.00	0.0	1.00
rs2076212^*	Gly/Cys (G/T)	0.891	0.109	0.882	0.118	0.65	0.31	1.00
rs738409^*	Ile/Met (C/G)	0.733	0.267	0.788	0.212	0.023	5.14	0.19
rs5764034	C/A	0.622	0.378	0.597	0.403	0.34	0.67	0.99
rs2076211	C/T	0.792	0.208	0.848	0.152	0.016	5.87	0.13
rs2072907^*	G/C	0.759	0.241	0.835	0.165	0.0013	9.84	0.015
rs1010022	A/G	0.767	0.233	0.840	0.160	0.0023	9.09	0.021
rs3810622^*	T/C	0.601	0.399	0.552	0.448	0.082	3.01	0.52
rs2294919	C/T	0.780	0.220	0.748	0.252	0.22	1.87	0.79

SNP	Major/minor allele	Lean			Obese			McNeamar P value	χ²	Permutation P value
SNP	Major/minor allele			1	2	1	2	McNeamar P value	χ²	Permutation P value
rs9626055	C/T	0.979	0.021	0.979	0.021	1.00	0.0	1.00
rs2076212^*	Gly/Cys (G/T)	0.891	0.109	0.882	0.118	0.65	0.31	1.00
rs738409^*	Ile/Met (C/G)	0.733	0.267	0.788	0.212	0.023	5.14	0.19
rs5764034	C/A	0.622	0.378	0.597	0.403	0.34	0.67	0.99
rs2076211	C/T	0.792	0.208	0.848	0.152	0.016	5.87	0.13
rs2072907^*	G/C	0.759	0.241	0.835	0.165	0.0013	9.84	0.015
rs1010022	A/G	0.767	0.233	0.840	0.160	0.0023	9.09	0.021
rs3810622^*	T/C	0.601	0.399	0.552	0.448	0.082	3.01	0.52
rs2294919	C/T	0.780	0.220	0.748	0.252	0.22	1.87	0.79

Data are presented as frequency. P values calculated using McNemar test. P values <0.05 are considered significant. 1, major allele; 2, minor allele.

Predicted tagSNPs using the Tagger program (Paul de Bakker; http://www.broad.mit.edu/mpg/tagger/).