Metabolic parameters during the basal period (after pretreatment) in control (saline), IL-6–treated, IL-6–and IL-10–co-treated, lipid-infused, and lipid- and IL-10–co-treated groups
. | n . | Body weight (g) . | Basal period . | . | . | ||
---|---|---|---|---|---|---|---|
. | . | . | Plasma glucose (mmol/l) . | Plasma insulin (pmol/l) . | Plasma fatty acids (mmol/l) . | ||
Control | 8 | 24 ± 1 | 9.1 ± 0.5 | 130 ± 15 | 1.2 ± 0.1 | ||
IL-6–treated | 5 | 22 ± 2 | 7.9 ± 0.5 | 119 ± 29 | 0.9 ± 0.1 | ||
IL-6–and IL-10–co-treated | 7 | 22 ± 0 | 7.9 ± 0.7 | 86 ± 10* | 1.1 ± 0.1 | ||
Lipid-infused | 5 | 27 ± 1 | 6.9 ± 0.4* | 110 ± 18 | 2.1 ± 0.5* | ||
Lipid- and IL-10–co-treated | 5 | 27 ± 2 | 7.2 ± 0.3* | 92 ± 15 | 1.9 ± 0.2* |
. | n . | Body weight (g) . | Basal period . | . | . | ||
---|---|---|---|---|---|---|---|
. | . | . | Plasma glucose (mmol/l) . | Plasma insulin (pmol/l) . | Plasma fatty acids (mmol/l) . | ||
Control | 8 | 24 ± 1 | 9.1 ± 0.5 | 130 ± 15 | 1.2 ± 0.1 | ||
IL-6–treated | 5 | 22 ± 2 | 7.9 ± 0.5 | 119 ± 29 | 0.9 ± 0.1 | ||
IL-6–and IL-10–co-treated | 7 | 22 ± 0 | 7.9 ± 0.7 | 86 ± 10* | 1.1 ± 0.1 | ||
Lipid-infused | 5 | 27 ± 1 | 6.9 ± 0.4* | 110 ± 18 | 2.1 ± 0.5* | ||
Lipid- and IL-10–co-treated | 5 | 27 ± 2 | 7.2 ± 0.3* | 92 ± 15 | 1.9 ± 0.2* |
Data are means ± SE.
P < 0.05 vs. control mice by Duncan’s multiple range test.