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TABLE 1

Metabolic parameters during the basal period (after pretreatment) in control (saline), IL-6–treated, IL-6–and IL-10–co-treated, lipid-infused, and lipid- and IL-10–co-treated groups

nBody weight (g)Basal period
Plasma glucose (mmol/l)Plasma insulin (pmol/l)Plasma fatty acids (mmol/l)
Control 24 ± 1 9.1 ± 0.5 130 ± 15 1.2 ± 0.1 
IL-6–treated 22 ± 2 7.9 ± 0.5 119 ± 29 0.9 ± 0.1 
IL-6–and IL-10–co-treated 22 ± 0 7.9 ± 0.7 86 ± 10* 1.1 ± 0.1 
Lipid-infused 27 ± 1 6.9 ± 0.4* 110 ± 18 2.1 ± 0.5* 
Lipid- and IL-10–co-treated 27 ± 2 7.2 ± 0.3* 92 ± 15 1.9 ± 0.2* 
nBody weight (g)Basal period
Plasma glucose (mmol/l)Plasma insulin (pmol/l)Plasma fatty acids (mmol/l)
Control 24 ± 1 9.1 ± 0.5 130 ± 15 1.2 ± 0.1 
IL-6–treated 22 ± 2 7.9 ± 0.5 119 ± 29 0.9 ± 0.1 
IL-6–and IL-10–co-treated 22 ± 0 7.9 ± 0.7 86 ± 10* 1.1 ± 0.1 
Lipid-infused 27 ± 1 6.9 ± 0.4* 110 ± 18 2.1 ± 0.5* 
Lipid- and IL-10–co-treated 27 ± 2 7.2 ± 0.3* 92 ± 15 1.9 ± 0.2* 

Data are means ± SE.

*

P < 0.05 vs. control mice by Duncan’s multiple range test.

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