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TABLE 3

Markers of cardiovascular risks and oxidative stress at admission and resolution of hyperglycemic crisis

Lean DKA
Obese DKA
Obese hyperglycemia
Lean controlObese control
AdmissionResolutionAdmissionResolutionAdmissionResolution
CRP (mg/l) 51 ± 3 28 ± 1* 59 ± 13 34 ± 9* 28 ± 6 13 ± 3* 1 ± 0.2* 2 ± 0.4* 
Homocysteine (μmol/l) 18.8 ± 0.8 14.8 ± 0.7* 23.6 ± 3.6 21.6 ± 2.8 14.8 ± 1.6 12.4 ± 1.2* 7.2 ± 0.4* 8.8 ± 1.2* 
FFA (mmol/l) 1.6 ± 0.1 0.6 ± 0.1* 1.4 ± 0.1 0.7 ± 0.1* 1.2 ± 0.2 0.8 ± 0.1* 0.5 ± 0.1* 0.7 ± 0.1* 
DCF (μmol/l) 8.6 ± 0.8 3.7 ± 0.5* 8.9 ± 1.2 4.1 ± 0.7* 7.8 ± 0.6 3.8 ± 0.5* 2.3 ± 0.4* 3.1 ± 0.6* 
TBA (μmol/l) 3.8 ± 0.7 1.3 ± 0.4* 4.0 ± 0.6 1.6 ± 0.2* 3.3 ± 0.5 1.5 ± 0.4* 0.8 ± 0.1* 0.9 ± 0.1* 
PAI-1 (ng/ml) 42.1 ± 12.2 4.2 ± 2.1* 40.4 ± 12.4 13.0 ± 3.4* 35.4 ± 9.3 7.3 ± 2.4* 1.4 ± 0.2* 2.5 ± 0.4* 
Lean DKA
Obese DKA
Obese hyperglycemia
Lean controlObese control
AdmissionResolutionAdmissionResolutionAdmissionResolution
CRP (mg/l) 51 ± 3 28 ± 1* 59 ± 13 34 ± 9* 28 ± 6 13 ± 3* 1 ± 0.2* 2 ± 0.4* 
Homocysteine (μmol/l) 18.8 ± 0.8 14.8 ± 0.7* 23.6 ± 3.6 21.6 ± 2.8 14.8 ± 1.6 12.4 ± 1.2* 7.2 ± 0.4* 8.8 ± 1.2* 
FFA (mmol/l) 1.6 ± 0.1 0.6 ± 0.1* 1.4 ± 0.1 0.7 ± 0.1* 1.2 ± 0.2 0.8 ± 0.1* 0.5 ± 0.1* 0.7 ± 0.1* 
DCF (μmol/l) 8.6 ± 0.8 3.7 ± 0.5* 8.9 ± 1.2 4.1 ± 0.7* 7.8 ± 0.6 3.8 ± 0.5* 2.3 ± 0.4* 3.1 ± 0.6* 
TBA (μmol/l) 3.8 ± 0.7 1.3 ± 0.4* 4.0 ± 0.6 1.6 ± 0.2* 3.3 ± 0.5 1.5 ± 0.4* 0.8 ± 0.1* 0.9 ± 0.1* 
PAI-1 (ng/ml) 42.1 ± 12.2 4.2 ± 2.1* 40.4 ± 12.4 13.0 ± 3.4* 35.4 ± 9.3 7.3 ± 2.4* 1.4 ± 0.2* 2.5 ± 0.4* 

Data are means ± SE.

*

P < 0.01 vs. lean DKA on admission;

P < 0.05 vs. admission value of each group.

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