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TABLE 3

Clinical characteristics of type 2 diabetic patients divided into groups on the basis of genotype

Pro/Pro (82.1%)Pro/Leu (17.9%)P
n (M/F) 151 (84/67) 33 (18/15) NS 
Age (years) 63.8 ± 9.4 63.4 ± 8.9 NS 
Maximum BMI (kg/m225.9 ± 2.6 26.2 ± 2.3 NS 
HbAlc (%) 7.3 ± 1.3 7.5 ± 1.2 NS 
Age at diagnosis (years) 44.8 ± 8.6 44.3 ± 7.8 NS 
Duration of diabetes (years) 18.7 ± 9.6 19.2 ± 8.1 NS 
Family history of diabetes 90 (59.6) 19 (57.6) NS 
Mode of treatment    
    Diet or OHA 100 (66.2) 19 (57.6) NS 
    Insulin 51 (33.8) 14 (42.4) NS 
Hypertension 62 (41.1) 15 (45.5) NS 
Hyperlipidemia 61 (40.4) 12 (35.3) NS 
Nephropathy 42 (27.8) 11 (33.3) NS 
Retinopathy 65 (43.0) 16 (48.5) NS 
Pro/Pro (82.1%)Pro/Leu (17.9%)P
n (M/F) 151 (84/67) 33 (18/15) NS 
Age (years) 63.8 ± 9.4 63.4 ± 8.9 NS 
Maximum BMI (kg/m225.9 ± 2.6 26.2 ± 2.3 NS 
HbAlc (%) 7.3 ± 1.3 7.5 ± 1.2 NS 
Age at diagnosis (years) 44.8 ± 8.6 44.3 ± 7.8 NS 
Duration of diabetes (years) 18.7 ± 9.6 19.2 ± 8.1 NS 
Family history of diabetes 90 (59.6) 19 (57.6) NS 
Mode of treatment    
    Diet or OHA 100 (66.2) 19 (57.6) NS 
    Insulin 51 (33.8) 14 (42.4) NS 
Hypertension 62 (41.1) 15 (45.5) NS 
Hyperlipidemia 61 (40.4) 12 (35.3) NS 
Nephropathy 42 (27.8) 11 (33.3) NS 
Retinopathy 65 (43.0) 16 (48.5) NS 

Data are means ± SD or n (%). Values compared by an unpaired Student’s t test, Mann-Whitney U test, or χ2 test. OHA, oral hypoglycemic agent.

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