Plasma glucose, insulin, NEFA, and triglyceride concentrations after an overnight fast and at the end of the 80 mU · m–2 · min–1 hyperinsulinemic-euglycemic clamps in 8 normal women and 10 normal men in the absence and presence of an infusion of Intralipid and heparin
| . | Women (n = 8) . | Men (n = 10) . | ||
|---|---|---|---|---|
| Control . | Lipid . | Control . | Lipid . | |
| Plasma glucose (mmol/l) | ||||
| Fasting | 4.9 ± 0.2 | 4.8 ± 0.1 | 4.9 ± 0.1 | 5.0 ± 0.1 |
| End of clamp | 4.8 ± 0.1 | 4.9 ± 0.1 | 5.0 ± 0.0 | 5.1 ± 0.0 |
| Plasma insulin (mU/l) | ||||
| Fasting | 8.9 ± 1.5 | 9.6 ± 2.0 | 7.0 ± 1.7 | 7.8 ± 1.6 |
| End of clamp | 123 ± 9 | 128 ± 18 | 118 ± 7 | 117 ± 8 |
| Plasma NEFA (μmol/l) | ||||
| Fasting | 535 ± 81 | 1,148 ± 75* | 351 ± 51 | 1,018 ± 60* |
| End of clamp | 24 ± 5 | 809 ± 105* | 15 ± 4 | 780 ± 80* |
| Plasma triglyceride (mg/dl) | ||||
| Fasting | 145 ± 41 | 321 ± 70† | 104 ± 21 | 223 ± 36* |
| End of clamp | 97 ± 36 | 317 ± 80‡ | 71 ± 20 | 277 ± 51* |
| . | Women (n = 8) . | Men (n = 10) . | ||
|---|---|---|---|---|
| Control . | Lipid . | Control . | Lipid . | |
| Plasma glucose (mmol/l) | ||||
| Fasting | 4.9 ± 0.2 | 4.8 ± 0.1 | 4.9 ± 0.1 | 5.0 ± 0.1 |
| End of clamp | 4.8 ± 0.1 | 4.9 ± 0.1 | 5.0 ± 0.0 | 5.1 ± 0.0 |
| Plasma insulin (mU/l) | ||||
| Fasting | 8.9 ± 1.5 | 9.6 ± 2.0 | 7.0 ± 1.7 | 7.8 ± 1.6 |
| End of clamp | 123 ± 9 | 128 ± 18 | 118 ± 7 | 117 ± 8 |
| Plasma NEFA (μmol/l) | ||||
| Fasting | 535 ± 81 | 1,148 ± 75* | 351 ± 51 | 1,018 ± 60* |
| End of clamp | 24 ± 5 | 809 ± 105* | 15 ± 4 | 780 ± 80* |
| Plasma triglyceride (mg/dl) | ||||
| Fasting | 145 ± 41 | 321 ± 70† | 104 ± 21 | 223 ± 36* |
| End of clamp | 97 ± 36 | 317 ± 80‡ | 71 ± 20 | 277 ± 51* |
Data are means ± SE.
P < 0.001,
P < 0.01,
P < 0.005 compared with the control study.