American Diabetes Association

TABLE 3

EGP and R_d in the basal state and during the last 40 min of the 80 mU · m^–2 · min^–1 hyperinsulinemic-euglycemic clamps in the 10 men and 8 women in the absence (control) and presence of an infusion of Intralipid and heparin (lipid) to raise plasma NEFA levels

	Women		Men
	Control	Lipid	Control	Lipid
Basal
EGP (mg · kg^–1 · min^–1)	2.02 ± 0.08	2.01 ± 0.10	2.03 ± 0.10	2.13 ± 0.08
End of clamp
EGP (mg · kg^–1 · min^–1)	−0.02 ± 0.09	0.61 ± 0.16^*	−0.11 ± 0.09	0.58 ± 0.11^†
Glucose R_d (mg · kg^–1 · min^–1)	10.37 ± 1.11	9.89 ± 1.26	10.78 ± 0.52	8.37 ± 0.57^‡

	Women		Men
	Control	Lipid	Control	Lipid
Basal
EGP (mg · kg^–1 · min^–1)	2.02 ± 0.08	2.01 ± 0.10	2.03 ± 0.10	2.13 ± 0.08
End of clamp
EGP (mg · kg^–1 · min^–1)	−0.02 ± 0.09	0.61 ± 0.16^*	−0.11 ± 0.09	0.58 ± 0.11^†
Glucose R_d (mg · kg^–1 · min^–1)	10.37 ± 1.11	9.89 ± 1.26	10.78 ± 0.52	8.37 ± 0.57^‡

Data are means ± SE. In the basal steady-state situation, glucose R_d is numerically equivalent to EGP.

P < 0.01,

†

P < 0.002,

‡

P < 0.001 compared with the control study.

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