American Diabetes Association

TABLE 3

Liver net glycogen deposited, glucose-6-phosphate, fructose-6-phosphate, glycogen synthase (activity ratio), and glycogen phosphorylase (activity ratio)

	Saline	AICAR1	AICAR2
Net glycogen deposition (mg/g tissue)	4.2 ± 0.7	2.3 ± 0.5^*	1.0 ± 0.1^*^†
Glycogen synthase (activity ratio)	0.20 ± 0.03	0.24 ± 0.02	0.20 ± 0.01
Glycogen phosphorylase (activity ratio)	0.60 ± 0.04	0.70 ± 0.06	0.71 ± 0.05
Glucose-6-phosphate (mg/100 g tissue)	5.2 ± 0.8	12.1 ± 1.8^*	12.0 ± 4.1^*
Fructose-6-phosphate (mg/100 g tissue)	1.9 ± 0.2	3.6 ± 0.7^*	3.6 ± 1.2^*

	Saline	AICAR1	AICAR2
Net glycogen deposition (mg/g tissue)	4.2 ± 0.7	2.3 ± 0.5^*	1.0 ± 0.1^*^†
Glycogen synthase (activity ratio)	0.20 ± 0.03	0.24 ± 0.02	0.20 ± 0.01
Glycogen phosphorylase (activity ratio)	0.60 ± 0.04	0.70 ± 0.06	0.71 ± 0.05
Glucose-6-phosphate (mg/100 g tissue)	5.2 ± 0.8	12.1 ± 1.8^*	12.0 ± 4.1^*
Fructose-6-phosphate (mg/100 g tissue)	1.9 ± 0.2	3.6 ± 0.7^*	3.6 ± 1.2^*

Data are means ± SE.

*

P ≤ 0.05 vs. saline;

†

P ≤ 0.05 vs. AICAR1.