Stereological estimate of the total number of neurons, volume, and cell density in the septal CA1 of adult male rats in sham-operated control and hypoglycemia groups
| . | Sham . | HG-2W . | HG-4W . |
|---|---|---|---|
| Cell number (×104) | 20.5 ± 0.09 | 5.19 ± 1.52* | 5.95 ± 1.27* |
| Volume (mm3) | 0.66 ± 0.03 | 0.27 ± 0.03† | 0.39 ± 0.02† |
| Cell density (×105 cells/mm3) | 3.14 ± 0.03 | 1.76 ± 0.26† | 1.48 ± 0.24† |
| . | Sham . | HG-2W . | HG-4W . |
|---|---|---|---|
| Cell number (×104) | 20.5 ± 0.09 | 5.19 ± 1.52* | 5.95 ± 1.27* |
| Volume (mm3) | 0.66 ± 0.03 | 0.27 ± 0.03† | 0.39 ± 0.02† |
| Cell density (×105 cells/mm3) | 3.14 ± 0.03 | 1.76 ± 0.26† | 1.48 ± 0.24† |
Data are means ± SD per hemisphere. n = 4 in sham-operated control group (Sham) and n = 7 in each hypoglycemia group (HG). An optical fractionator was used to estimate the total numbers of NeuN immunoreactive cells in the septal CA1. Significant difference in cell number, volume, and density was found at 2 weeks (HG-2W) and 4 weeks (HG-4W) after hypoglycemia when compared with controls, as indicated.
P < 0.001,
P < 0.005.