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Table 1—

Baseline characteristics of normo- and microalbuminuric patients of the Casale Monferrato Study recruited for follow-up

NormoalbuminuricMicroalbuminuricP
n 677 426  
Age (years) 67.2 ± 10.0 67.9 ± 10.6 0.22 
Men 273 (40.3) 204 (47.9) 0.01 
Duration of diabetes (years) 9.8 ± 6.3 11.1 ± 7.0 0.001 
BMI (kg/m227.4 ± 4.8 27.8 ± 4.8 0.20 
Antidiabetic treatment    
 Diet 98 (14.5) 30 (7.1) <0.0001 
 Oral drugs 496 (73.5) 299 (70.7)  
 Insulin 81 (12.0) 94 (22.2)  
CHD 123 (21.5) 84 (23.7) 0.43 
Smoker 89 (13.4) 60 (14.4) 0.02 
Ex-smoker 119 (18.0) 103 (24.7)  
Nonsmoker 454 (68.6) 254 (60.9)  
Hypertension 554 (81.8) 363 (85.2) 0.08 
Systolic blood pressure (mmHg) 153.1 ± 21.1 156.1 ± 22.5 0.03 
Diastolic blood pressure (mmHg) 87.0 ± 10.0 88.3 ± 10.7 0.03 
Treatment with ACE inhibitors 140 (20.7) 94 (22.1) 0.58 
HbA1c (%) 7.8 ± 2.3 8.4 ± 2.3 <0.0001 
Total cholesterol (mmol/l) 5.81 ± 1.20 5.80 ± 1.25 0.85 
HDL cholesterol (mmol/l) 1.46 ± 0.43 1.42 ± 0.52 0.26 
Triglycerides (mmol/l) 1.44 (1.02–1.91) 1.55 (1.07–2.15) 0.02 
ApoA1 (mg/dl) 137.1 ± 35.5 131.8 ± 29.8 0.01 
ApoB (mg/dl) 101.6 ± 35.0 102.2 ± 38.6 0.79 
Fibrinogen (g/l) 3.55 ± 0.87 3.69 ± 0.97 0.01 
Uric acid (μmol/l) 313 ± 92 323 ± 92 0.09 
Creatinine (μmol/l) 88 (74–97) 90 (80–104) 0.007 
NormoalbuminuricMicroalbuminuricP
n 677 426  
Age (years) 67.2 ± 10.0 67.9 ± 10.6 0.22 
Men 273 (40.3) 204 (47.9) 0.01 
Duration of diabetes (years) 9.8 ± 6.3 11.1 ± 7.0 0.001 
BMI (kg/m227.4 ± 4.8 27.8 ± 4.8 0.20 
Antidiabetic treatment    
 Diet 98 (14.5) 30 (7.1) <0.0001 
 Oral drugs 496 (73.5) 299 (70.7)  
 Insulin 81 (12.0) 94 (22.2)  
CHD 123 (21.5) 84 (23.7) 0.43 
Smoker 89 (13.4) 60 (14.4) 0.02 
Ex-smoker 119 (18.0) 103 (24.7)  
Nonsmoker 454 (68.6) 254 (60.9)  
Hypertension 554 (81.8) 363 (85.2) 0.08 
Systolic blood pressure (mmHg) 153.1 ± 21.1 156.1 ± 22.5 0.03 
Diastolic blood pressure (mmHg) 87.0 ± 10.0 88.3 ± 10.7 0.03 
Treatment with ACE inhibitors 140 (20.7) 94 (22.1) 0.58 
HbA1c (%) 7.8 ± 2.3 8.4 ± 2.3 <0.0001 
Total cholesterol (mmol/l) 5.81 ± 1.20 5.80 ± 1.25 0.85 
HDL cholesterol (mmol/l) 1.46 ± 0.43 1.42 ± 0.52 0.26 
Triglycerides (mmol/l) 1.44 (1.02–1.91) 1.55 (1.07–2.15) 0.02 
ApoA1 (mg/dl) 137.1 ± 35.5 131.8 ± 29.8 0.01 
ApoB (mg/dl) 101.6 ± 35.0 102.2 ± 38.6 0.79 
Fibrinogen (g/l) 3.55 ± 0.87 3.69 ± 0.97 0.01 
Uric acid (μmol/l) 313 ± 92 323 ± 92 0.09 
Creatinine (μmol/l) 88 (74–97) 90 (80–104) 0.007 

Data are means ± SD, n (%), or medians (interquartile range).

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