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Table 2—

Results of conditional logistic regression analyses of variables associated with progression to overt nephropathy in the Casale Monferrato Study

OR (95% CI)
Duration (years)  
 <5.5 1.00 
 5.5–8.5 1.10 (0.67–1.80) 
 8.6–14.9 1.44 (0.89–2.35) 
 >14.9 1.39 (0.85–2.28) 
Hypertension  
 No 1.00 
 Yes 0.67 (0.35–1.28) 
Systolic blood pressure (mmHg)  
 <140 1.00 
 141–152 0.87 (0.47–1.60) 
 153–170 1.53 (0.87–2.68) 
 >170 1.21 (0.67–2.18) 
AER  
 Normoalbuminuria 1.00 
 Microalbuminuria 1.42 (0.98–2.06) 
HbA1c cumulative average (%)  
 <6.16 1.00 
 6.16–7.37 0.52 (0.31–0.88) 
 7.38–8.32 0.67 (0.40–1.12) 
 >8.32 1.26 (0.78–2.03) 
Fibrinogen (g/l)  
 <3.00 1.00 
 3.00–3.48 1.07 (0.63–1.83) 
 3.49–4.12 1.93 (1.18–3.16) 
 >4.12 1.54 (0.92–2.58) 
HDL cholesterol (mmol/l)  
 <1.14 1.00 
 1.14–1.34 0.56 (0.34–0.93) 
 1.35–1.60 0.55 (0.34–0.87) 
 >1.60 0.54 (0.33–0.89) 
ApoB (mg/dl)  
 <74 1.00 
 74–94 0.82 (0.48–1.40) 
 95–122 1.73 (1.05–2.87) 
 >122 1.34 (0.81–2.24) 
OR (95% CI)
Duration (years)  
 <5.5 1.00 
 5.5–8.5 1.10 (0.67–1.80) 
 8.6–14.9 1.44 (0.89–2.35) 
 >14.9 1.39 (0.85–2.28) 
Hypertension  
 No 1.00 
 Yes 0.67 (0.35–1.28) 
Systolic blood pressure (mmHg)  
 <140 1.00 
 141–152 0.87 (0.47–1.60) 
 153–170 1.53 (0.87–2.68) 
 >170 1.21 (0.67–2.18) 
AER  
 Normoalbuminuria 1.00 
 Microalbuminuria 1.42 (0.98–2.06) 
HbA1c cumulative average (%)  
 <6.16 1.00 
 6.16–7.37 0.52 (0.31–0.88) 
 7.38–8.32 0.67 (0.40–1.12) 
 >8.32 1.26 (0.78–2.03) 
Fibrinogen (g/l)  
 <3.00 1.00 
 3.00–3.48 1.07 (0.63–1.83) 
 3.49–4.12 1.93 (1.18–3.16) 
 >4.12 1.54 (0.92–2.58) 
HDL cholesterol (mmol/l)  
 <1.14 1.00 
 1.14–1.34 0.56 (0.34–0.93) 
 1.35–1.60 0.55 (0.34–0.87) 
 >1.60 0.54 (0.33–0.89) 
ApoB (mg/dl)  
 <74 1.00 
 74–94 0.82 (0.48–1.40) 
 95–122 1.73 (1.05–2.87) 
 >122 1.34 (0.81–2.24) 
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