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Table 2—

HRs of variables possibly predictive of survival of diabetic subjects on regular hemodialysis determined by Cox proportional hazard model

VariablesUnadjusted
Adjusted for multivariates*
HR95% CIP valueHR95% CIP value
Age at entry (years) 1.045 1.018–1.072 0.0009 — — — 
Sex (female = 1) 0.905 0.536–1.530 0.710 — — — 
Duration of hemodialysis (years) 1.001 0.995–1.007 0.855 — — — 
Existence of cardiac disease (no = 1) 1.767 1.110–2.814 0.017 — — — 
Glycemic control (A1C) group (good group = 1)       
    Fair group 1.030 0.557–1.904 0.925 1.317 0.695–2.495 0.399 
    Poor group 1.773 1.000–3.145 0.050 2.889 1.538–5.429 0.010 
Mean A1C (%) 1.134 0.981–1.311 0.088 1.260 1.081–1.468 0.003 
Systolic blood pressure (mmHg) 0.983 0.970–0.995 0.007 0.990 0.997–1.003 0.121 
Diastolic blood pressure (mmHg) 0.963 0.935–0.992 0.014 0.984 0.952–1.017 0.338 
Cardiothoracic ratio (%) 1.040 0.959–1.128 0.340 0.992 0.901–1.093 0.876 
Creatinine (mg/dl) 0.947 0.866–1.036 0.231 0.921 0.825–1.029 0.148 
Sodium (mEq/l) 0.992 0.940–1.048 0.777 0.961 0.912–1.014 0.144 
Potassium (mEq/l) 0.849 0.643–1.123 0.251 0.867 0.643–1.169 0.349 
Total protein (g/dl) 0.848 0.530–1.357 0.492 0.855 0.527–1.386 0.525 
Albumin (g/dl) 0.229 0.086–0.606 0.003 0.373 0.130–1.069 0.066 
Hemoglobin (g/dl) 1.006 0.840–1.205 0.946 1.034 0.853–1.253 0.732 
Total cholesterol (mg/dl) 1.001 0.996–1.007 0.643 1.003 0.997–1.009 0.367 
Uric acid (mg/dl) 1.004 0.827–1.317 0.720 1.027 0.805–1.311 0.829 
VariablesUnadjusted
Adjusted for multivariates*
HR95% CIP valueHR95% CIP value
Age at entry (years) 1.045 1.018–1.072 0.0009 — — — 
Sex (female = 1) 0.905 0.536–1.530 0.710 — — — 
Duration of hemodialysis (years) 1.001 0.995–1.007 0.855 — — — 
Existence of cardiac disease (no = 1) 1.767 1.110–2.814 0.017 — — — 
Glycemic control (A1C) group (good group = 1)       
    Fair group 1.030 0.557–1.904 0.925 1.317 0.695–2.495 0.399 
    Poor group 1.773 1.000–3.145 0.050 2.889 1.538–5.429 0.010 
Mean A1C (%) 1.134 0.981–1.311 0.088 1.260 1.081–1.468 0.003 
Systolic blood pressure (mmHg) 0.983 0.970–0.995 0.007 0.990 0.997–1.003 0.121 
Diastolic blood pressure (mmHg) 0.963 0.935–0.992 0.014 0.984 0.952–1.017 0.338 
Cardiothoracic ratio (%) 1.040 0.959–1.128 0.340 0.992 0.901–1.093 0.876 
Creatinine (mg/dl) 0.947 0.866–1.036 0.231 0.921 0.825–1.029 0.148 
Sodium (mEq/l) 0.992 0.940–1.048 0.777 0.961 0.912–1.014 0.144 
Potassium (mEq/l) 0.849 0.643–1.123 0.251 0.867 0.643–1.169 0.349 
Total protein (g/dl) 0.848 0.530–1.357 0.492 0.855 0.527–1.386 0.525 
Albumin (g/dl) 0.229 0.086–0.606 0.003 0.373 0.130–1.069 0.066 
Hemoglobin (g/dl) 1.006 0.840–1.205 0.946 1.034 0.853–1.253 0.732 
Total cholesterol (mg/dl) 1.001 0.996–1.007 0.643 1.003 0.997–1.009 0.367 
Uric acid (mg/dl) 1.004 0.827–1.317 0.720 1.027 0.805–1.311 0.829 

Existence of cardiac diseases: existence of coronary artery disease and/or echocardiographic abnormalities.

*

Adjusted for age, sex, and duration of hemodialysis and existence of cardiac disease. The HR for each variable is expressed per increment of 1 unit of each variable. That for glycemic control group (A1C group) refers to good A1C group as 1, and that for sex refers to females as 1.

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