Multivariate Cox regression models relating glycemia to microvascular complications
| Variable . | Nephropathy . | P value . | Retinopathy . | P value . |
|---|---|---|---|---|
| Model 1 | ||||
| MBG (AUC) | 1.03 (0.96–1.11) | 0.42 | 1.15 (1.06–1.25) | <0.0001 |
| SD MBG (AUC) | 0.96 (0.82–1.11) | 0.57 | 0.97 (0.81–1.16) | 0.72 |
| SD (within day) | 1.01 (0.99–1.03) | 0.32 | 1.02 (0.99–1.04) | 0.18 |
| Model 2 | ||||
| Preprandial | 1.08 (0.94–1.24) | 0.28 | 1.11 (0.95–1.30) | 0.18 |
| Postprandial | 0.99 (0.89–1.12) | 0.83 | 1.08 (0.94–1.24) | 0.31 |
| Variable . | Nephropathy . | P value . | Retinopathy . | P value . |
|---|---|---|---|---|
| Model 1 | ||||
| MBG (AUC) | 1.03 (0.96–1.11) | 0.42 | 1.15 (1.06–1.25) | <0.0001 |
| SD MBG (AUC) | 0.96 (0.82–1.11) | 0.57 | 0.97 (0.81–1.16) | 0.72 |
| SD (within day) | 1.01 (0.99–1.03) | 0.32 | 1.02 (0.99–1.04) | 0.18 |
| Model 2 | ||||
| Preprandial | 1.08 (0.94–1.24) | 0.28 | 1.11 (0.95–1.30) | 0.18 |
| Postprandial | 0.99 (0.89–1.12) | 0.83 | 1.08 (0.94–1.24) | 0.31 |
Data are HR (95% CI). Both models adjusted for baseline covariates. MBG (AUC), AUC of seven-point blood glucose profile (mmol/l); SD MBG (AUC), SD of between-visit AUC; SD (within-day), SD of glucose profile.