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Table 2—

Multivariate Cox regression models relating glycemia to microvascular complications

VariableNephropathyP valueRetinopathyP value
Model 1     
    MBG (AUC) 1.03 (0.96–1.11) 0.42 1.15 (1.06–1.25) <0.0001 
    SD MBG (AUC) 0.96 (0.82–1.11) 0.57 0.97 (0.81–1.16) 0.72 
    SD (within day) 1.01 (0.99–1.03) 0.32 1.02 (0.99–1.04) 0.18 
Model 2     
    Preprandial 1.08 (0.94–1.24) 0.28 1.11 (0.95–1.30) 0.18 
    Postprandial 0.99 (0.89–1.12) 0.83 1.08 (0.94–1.24) 0.31 
VariableNephropathyP valueRetinopathyP value
Model 1     
    MBG (AUC) 1.03 (0.96–1.11) 0.42 1.15 (1.06–1.25) <0.0001 
    SD MBG (AUC) 0.96 (0.82–1.11) 0.57 0.97 (0.81–1.16) 0.72 
    SD (within day) 1.01 (0.99–1.03) 0.32 1.02 (0.99–1.04) 0.18 
Model 2     
    Preprandial 1.08 (0.94–1.24) 0.28 1.11 (0.95–1.30) 0.18 
    Postprandial 0.99 (0.89–1.12) 0.83 1.08 (0.94–1.24) 0.31 

Data are HR (95% CI). Both models adjusted for baseline covariates. MBG (AUC), AUC of seven-point blood glucose profile (mmol/l); SD MBG (AUC), SD of between-visit AUC; SD (within-day), SD of glucose profile.

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