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TABLE 1

Summary of islet viability after in vitro challenges

TreatmentPercentage of viable islets*
UnmodifiedAd-LacZAd-MnSOD
Alloxan 10% (n = 112) 4% (n = 102) 95% (n = 110) 
SNAP 15% (n = 105) 20% (n = 100) 22% (n = 90) 
Cytokines 20% (n = 98) 29% (n = 104) 66% (n = 96) 
TreatmentPercentage of viable islets*
UnmodifiedAd-LacZAd-MnSOD
Alloxan 10% (n = 112) 4% (n = 102) 95% (n = 110) 
SNAP 15% (n = 105) 20% (n = 100) 22% (n = 90) 
Cytokines 20% (n = 98) 29% (n = 104) 66% (n = 96) 
*

Percentage of islets was determined by dividing the number of viable islets remaining after treatment (those with <500 dead cells) divided by the total number of islets tested per treatment (n). Results are from three separate experiments of the three different islet groups.

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