Body weight, kidney weight, SBP, and plasma glucose of control and diabetic transgenic (mRen-2)27 rats treated for 6 months with LY333531
| . | Body weight (g) . | Kidney weight (g) . | SBP (mmHg) . | Glucose (mmol/l) . | Albuminuria (mg/24 h) . |
|---|---|---|---|---|---|
| Control | 562 ± 23 | 2.31 ± 0.12 | 217 ± 9 | 4.4 ± 0.3 | 5.9×/÷0.4 |
| Diabetic | 490 ± 10† | 2.92 ± 0.09* | 224 ± 6 | 21.7 ± 1.01† | 49.4×/÷1.8† |
| Diabetic + LY | 472 ± 15† | 2.73 ± 0.13* | 221 ± 4 | 20.8 ± 0.7† | 15.6×/÷1.9‡‡ |
| . | Body weight (g) . | Kidney weight (g) . | SBP (mmHg) . | Glucose (mmol/l) . | Albuminuria (mg/24 h) . |
|---|---|---|---|---|---|
| Control | 562 ± 23 | 2.31 ± 0.12 | 217 ± 9 | 4.4 ± 0.3 | 5.9×/÷0.4 |
| Diabetic | 490 ± 10† | 2.92 ± 0.09* | 224 ± 6 | 21.7 ± 1.01† | 49.4×/÷1.8† |
| Diabetic + LY | 472 ± 15† | 2.73 ± 0.13* | 221 ± 4 | 20.8 ± 0.7† | 15.6×/÷1.9‡‡ |
Values are expressed as means ± SE except for albuminuria, which is expressed as geometric mean ×/÷ tolerance factor; n = 8 rats per group.
P < 0.05 when compared with respective nondiabetic rats;
P < 0.01 when compared with respective nondiabetic rats;
P < 0.05 versus untreated diabetic rats. LY, LY333531.